Navegando por Palavras-chave "High-intensity resistance training"
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- ItemSomente MetadadadosUnraveling the role of high-intensity resistance training on left ventricle proteome: Is there a shift towards maladaptation?(Pergamon-Elsevier Science Ltd, 2016) Dantas, Patricia Sousa [UNIFESP]; Sakata, Maisa Mayumi [UNIFESP]; Perez, Juliana Dineia [UNIFESP]; Watanabe, Regina Lucia Harumi [UNIFESP]; Bizerra, Fernando Cesar [UNIFESP]; Neves, Vander Jose das; Guzzoni, Vinicius; Marcondes, Fernanda Klein; Casarini, Dulce Elena [UNIFESP]; Cunha, Tatiana Sousa [UNIFESP]High-intensity resistance training (RT) induces adaptations that improve physiological function. However, high intensity, volume and/or frequency may lead to injury and other health issues such as adverse cardiac effects. The aim of this study was to evaluate the effect of RT on left ventricle proteome, and to identify the pathways involved on the harmful adaptations induced by this protocol. Male Wistar rats were randomized into 2 groups: Trained (T) and Sedentary (S). Animals from T group were trained for 6 weeks, and then all the animals were sacrificed and left ventricle was isolated for analysis. We identified 955 proteins, and 93 proteins were considered