Navegando por Palavras-chave "Glomerulopatia Membranosa Primária"

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    Anticorpos Anti-Receptor De Fosfolipase A2 Em Pacientes Brasileiros Com Glomerulopatias
    (Universidade Federal de São Paulo (UNIFESP), 2018-12-20) Santos Neto, Cicero De Oliveira [UNIFESP]; Kirsztajn, Gianna Mastroianni [UNIFESP]
    Introduction: Recently Great Progress Has Been Made In Understanding The Pathogenesis Of Membranous Glomerulopathy With The Discovery Of Antibodies Against The M-Type Receptor Of Phospholipase A2 (M-Type Phospholipase A2 Receptor, Pla2r) In Serum And Immunocomplexes In Glomeruli In Most Cases Of Primary Membranous Glomerulopathy In Adult Patients. Objectives: To Evaluate Levels Of Anti-Pla2r Antibodies In Brazilian Patients With Membranous Glomerulopathy, In Order To Verify In This Population The Possible Association Of These Autoantibodies With Their Primary Form In Situations Of Active Or Inactive Glomerular Disease, Using As Controls Secondary Membranous Glomerulopathy And Other Proteinuric Glomerulopathies; To Establish Sensitivity, Specificity And Predictive Values Of The Method Used For The Determination Of Anti-Pla2r Antibodies. Material And Methods: We Included In This Study 117 Patients Followed At The Unifesp - Epm Glomerulonephritis Clinic That Presented Glomerulopathies With Diagnosis Confirmed By