Navegando por Palavras-chave "Fator V de Leiden"

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    Trombose venosa em criança
    (Sociedade Brasileira de Patologia ClínicaSociedade Brasileira de PatologiaSociedade Brasileira de Citopatologia, 2009-06-01) Santos, Maria Emília dos; Nascimento Júnior, Braz José do [UNIFESP]; Correia, Maria da Conceição Barros; Lima, Vera Lúcia de Menezes; Abib, Simone de Campos Vieira [UNIFESP]; Coelho, Luana Cassandra Breitenbach Barroso; Fundação de Hematologia e Hemoterapia de Pernambuco; Universidade Federal de São Paulo (UNIFESP); UFPE; UFPE Departamento de Bioquímica
    The incidence of deep venous thrombosis (DVT) in children (0-18 years old) is low. The aim of this study was to investigate the case of a 12 year-old child that had DVT after a trauma. Protein C and protein S activities, antithrombin and resistance to activated protein C were analyzed in coagulometer. Factor V Leiden (FVL) was studied. The patient and his father were heterozygotes for FVL. His mother was normal homozygote. We concluded that the presence of FVL associated with other medical conditions tends to multiply the occurrence of thrombosis, which is a multifactorial disease.