Navegando por Palavras-chave "Evoked Potentials, Auditory, Brain Stem"

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    Alterações auditivas e fenilcetonúria: uma revisão sistemática
    (CEFAC Saúde e Educação, 2010-02-01) Mancini, Patrícia Cotta [UNIFESP]; Starling, Ana Lúcia Pimenta; Alves, Cláudia Fernanda Tolentino; Martins, Thaís Maria da Mata; Iorio, Maria Cecilia Martinelli [UNIFESP]; Universidade Federal de Minas Gerais Curso de Graduação em Fonoaudiologia; Universidade Federal de Minas Gerais Faculdade de Medicina Departamento de Pediatria; Universidade Federal de São Paulo (UNIFESP)
    BACKGROUND: phenylketonuria is a genetic disorder that causes biochemical alterations, leading to a deficiency in the synthesis of proteins and neurotransmitters and thereby hindering the myelination process. Structural and functional changes in myelin can alter neural conductivity patterns and or reduce synaptic connection in individuals with phenylketonuria. Essentially, a dietary treatment should be implemented in the first weeks of life in order to avoid clinical and biochemical manifestations of the disease. When diet is continually maintained, children with phenylketonuria show normal development. However, deficits in executive functions, interhemispherical interaction, language and memory have been observed even in children with early treatment and appropriate diet. Some researches were carried out for investigating the relationship between phenylketonuria and alterations in the hearing function. PURPOSE: to systematically review articles dedicated to the research of relationship between hearing disorders and hyperphenylalaninaemias, highlighting the classic phenylketonuria. The bibliographical references were obtained through research in the databases: Lilacs, Medline, Cochrane Library and Scielo and through search in the reference list of the identified and selected articles. CONCLUSION: the relationship among hyperphenylalaninaemias, including phenylketonuria, and hearing alterations is still controversial in the literature. It is suggested that more investigations as for the hearing function are necessary on those individuals in order to elucidate this possible relationship.
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    Estudo do efeito de supressão no potencial evocado auditivo de tronco encefálico
    (Pró-Fono Produtos Especializados para Fonoaudiologia Ltda., 2010-09-01) Matas, Carla Gentile [UNIFESP]; Silva, Fernanda Nivoloni O; Leite, Renata Aparecida; Samelli, Alessandra Giannella; Universidade Federal de São Paulo (UNIFESP); Universidade de São Paulo (USP)
    BACKGROUND: the suppression effect with contralateral white noise observed in the brainstem auditory evoked potential can be influenced by the efferent auditory system. AIM: to evaluate the suppression effect with contralateral white noise in the Brainstem Auditory Evoked Potential of individuals with normal hearing. METHODS: 25 individuals, ranging in age from 18 to 30 years, of both genders, were submitted to a clinical history questionnaire, inspection of the external auditory canal, conventional audiometry, speech audiometry and acoustic immittance measurements. Only individuals with normal hearing thresholds were selected. The selected individuals underwent brainstem auditory evoked potential testing with and without contralateral white noise. RESULTS: a significant statistical difference was observed between the situations with and without contralateral white noise, for wave I amplitude and waves III and V latencies. No statistical differences were observed for the interpeak latencies. CONCLUSION: the present study indicated increased latencies and reduced amplitudes of waves I, III and V with contralateral noise, when comparing the situations with and without noise. These results suggest a possible influence of the efferent auditory system on the response modulation of Brainstem auditory evoked potential when contralateral white noise is used.