Navegando por Palavras-chave "Evoked Potentials, Auditory"
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- ItemAcesso aberto (Open Access)Alterações auditivas e fenilcetonúria: uma revisão sistemática(CEFAC Saúde e Educação, 2010-02-01) Mancini, Patrícia Cotta [UNIFESP]; Starling, Ana Lúcia Pimenta; Alves, Cláudia Fernanda Tolentino; Martins, Thaís Maria da Mata; Iorio, Maria Cecilia Martinelli [UNIFESP]; Universidade Federal de Minas Gerais Curso de Graduação em Fonoaudiologia; Universidade Federal de Minas Gerais Faculdade de Medicina Departamento de Pediatria; Universidade Federal de São Paulo (UNIFESP)BACKGROUND: phenylketonuria is a genetic disorder that causes biochemical alterations, leading to a deficiency in the synthesis of proteins and neurotransmitters and thereby hindering the myelination process. Structural and functional changes in myelin can alter neural conductivity patterns and or reduce synaptic connection in individuals with phenylketonuria. Essentially, a dietary treatment should be implemented in the first weeks of life in order to avoid clinical and biochemical manifestations of the disease. When diet is continually maintained, children with phenylketonuria show normal development. However, deficits in executive functions, interhemispherical interaction, language and memory have been observed even in children with early treatment and appropriate diet. Some researches were carried out for investigating the relationship between phenylketonuria and alterations in the hearing function. PURPOSE: to systematically review articles dedicated to the research of relationship between hearing disorders and hyperphenylalaninaemias, highlighting the classic phenylketonuria. The bibliographical references were obtained through research in the databases: Lilacs, Medline, Cochrane Library and Scielo and through search in the reference list of the identified and selected articles. CONCLUSION: the relationship among hyperphenylalaninaemias, including phenylketonuria, and hearing alterations is still controversial in the literature. It is suggested that more investigations as for the hearing function are necessary on those individuals in order to elucidate this possible relationship.
- ItemAcesso aberto (Open Access)Estudo do padrão de normalidade do potencial evocado auditivo de adultos ouvintes normais por meio de um novo equipamento de diagnóstico desenvolvido(Universidade Federal de São Paulo (UNIFESP), 2010-02-24) Soares, Ilka do Amaral [UNIFESP]; Pereira, Liliane Desgualdo [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)Objective: To validate responses of the Auditory Brainstem Response (ABR) using a new equipment developed in Brazil. Method: The annalyses of the absolute latencies, inter slopes, and magnitude of the waves I and V, using a new equipment developed to asses the Experimental Group 1 (76 participants with normal hearing). Analysis of the ABR using the gold-standard equipment, EP15/Interacoustis, where performed in Gold Group 1 (15 participants with normal hearing) and Gold Group 2 (15 participants with sensorineural hearing loss). In order to assess the validity of the new equipment, analysis of the ABR were performed using the new equipment with participants of the Gold Group 1 to compare with participants from the Experimental Group 2, and with participants from the Gold Group 2 to compare with participants from the Experimental Group 3. The stimulus used to obtain the evocated responses was a non-filtrated click sound, with a duration of 100 μs and a total of 2,000 stimuli. All stimuli were given in the negative (rarefaction wave) polarities in a stimulation frequency of 13.1 clicks, with an intensity of 80 dB Nan, an interval of 10 milliseconds and a filter band-pass set between 100 and 3000Hz. The results were statistically analyzed considering a significance level of 0.05. Results: The means for the absolute latencies and inter slopes for the specific waves using the new equipment were: I=1.50, III=3.57, V=5.53, I-III=2.06, III-V=1.96 e I-V=4.02. Statistically significant gender differences were observed for the absolute latencies in wave III (p=0,000) and V (p=0,000) as well as for the inter slopes I-III (p=0,007) and I-V (p=0,001). The mean magnitude values for wave I and V were 0.384 μV and 0.825 μV, respectively. No statistically significant differences between the new equipment and the gold-standard were observed when comparing the results for absolute latencies and inter slopes in the same individual (with normal hearing or with sensorineural hearing loss). Conclusions: The components of the ABR assessed in adults with no hearing impairments using the new equipment were similar for both ears, with latencies significantly lower for women than for men. Moreover, the latencies of the ABR in the same individual (either normal or with sensorineural hearing loss) did not differ between the new equipment and the gold-standard equipament. In hearing loss of mild to moderate degree the most frequent finding on the ABR was the presence of Waves I, III, V and absolute latencies and inter slopes within normal limits. The referent values of normality for the ABR were obtained in adults with normal hearing.
- ItemAcesso aberto (Open Access)Treinamento auditivo formal em adultos com deficiência auditiva(Universidade Federal de São Paulo (UNIFESP), 2006-01-31) Gil, Daniela [UNIFESP]; Iorio, Maria Cecilia Martinelli [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)Objective: To verify the effects of a formal auditory training program in adult hearing aid users with mild to moderate sensorineural hearing loss using behavioral auditory processing tests, a self-report benefit scale and long latency auditory evoked potential – P300. Method: Fourteen intra-aural hearing aid users were divided into two groups: seven with auditory training and seven without auditory training. Subjects from experimental group have undergone a formal auditory training program with hearing aids, organized in eight sessions of 45 minutes each, twice a week, aiming at improving auditory closure, figure-to-ground for verbal and nonverbal sounds and temporal processing (frequency and duration of sounds) skills. The program itself and the activities within the session were proposed in progressive complexity in order to challenge the auditory system. Auditory training efficiency was verified by evaluating all subjects in two different occasions: pre and post-training in the Experimental Group and in the initial and final evaluations in the Control Group, including electrophysiologic and behavioral auditory processing evaluations and the application of the self-report benefit scale APHAB. Results: Neither amplitude and latency of P300 nor the behavioral central auditory tests used revealed significant differences for the right or left ears. In the post-training evaluation Experimental Group presented statistically significant reduction in P3 latency, improved performance in all behavioral auditory processing tests and higher benefit in noisy situations as demonstrated in the self-report benefit scale APHAB than the Control Group. Conclusions: We could conclude that formal auditory training in adult hearing aid users lead to reduction in P3 latency; improvements in memory for verbal and nonverbal sounds in sequence, auditory closure, figure-to-ground for verbal sounds and higher benefit in reverberant and noisy environments