Navegando por Palavras-chave "Estudos Multicêntricos como Assunto"
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- ItemSomente MetadadadosI RBH – Primeiro Registro Brasileiro de Hipertensão Arterial(Arquivos Brasileiros Cardiologia, 2016) Jardim, Paulo Cesar Brandao Veiga; Sebba Barroso de Souza, Weimar Kunz; Lopes, Renato Delascio [UNIFESP]; Brandao, Andrea Araujo; Malachias, Marcus Vinícius Bolívar; Gomes, Marco Mota; Moreno Junior, Heitor; Duarte Barbosa, Eduardo Costa; Póvoa, Rui Manuel dos Santos [UNIFESP]Background: A registry assessing the care of hypertensive patients in daily clinical practice in public and private centers in various Brazilian regions has not been conducted to date. Such analysis is important to elucidate the effectiveness of this care. Objective: To document the current clinical practice for the treatment of hypertension with identification of the profile of requested tests, type of administered treatment, level of blood pressure (BP) control, and adherence to treatment. Methods: National, observational, prospective, and multicenter study that will include patients older than 18 years with hypertension for at least 4 weeks, following up in public and private centers and after signing a consent form. The study will exclude patients undergoing dialysis, hospitalized in the previous 30 days, with class III or IV heart failure, pregnant or nursing, with severe liver disease, stroke or acute myocardial infarction in the past 30 days, or with diseases with a survival prognosis < 1 year. Evaluations will be performed at baseline and after 1 year of follow-up. The parameters that will be evaluated include anthropometric data, lifestyle habits, BP levels, lipid profile, metabolic syndrome, and adherence to treatment. The primary outcomes will be hospitalization due to hypertensive crisis, cardiocirculatory events, and cardiovascular death, while secondary outcomes will be hospitalization for heart failure and requirement of dialysis. A subgroup analysis of 15% of the sample will include noninvasive central pressure evaluation at baseline and study end. The estimated sample size is 3,000 individuals for a prevalence of 5%, sample error of 2%, and 95% confidence interval. Results: The results will be presented after the final evaluation, which will occur at the end of a 1-year follow-up. Conclusion: The analysis of this registry will improve the knowledge and optimize the treatment of hypertension in Brazil, as a way of modifying the prognosis of cardiovascular disease in the country.
- ItemAcesso aberto (Open Access)Perguntas mínimas para rastrear dependência em atividades da vida diária em idosos(Faculdade de Saúde Pública da Universidade de São Paulo, 2013-06-01) Ramos, Luiz Roberto [UNIFESP]; Andreoni, Solange [UNIFESP]; Coelho-Filho, João Macedo; Lima-Costa, Maria Fernanda; Matos, Divane Leite; Rebouças, Monica; Veras, Renato Peixoto [UNIFESP]; Universidade Federal de São Paulo (UNIFESP); Universidade Federal do Ceará. Fortaleza Faculdade de Medicina Departamento de Medicina Clínica; Fundação Oswaldo Cruz Centro de Pesquisas René Rachou; Universidade do Estado do Rio de Janeiro Universidade Aberta da Terceira IdadeOBJECTIVE:To analyze non-redundant questions on independence in activities of daily living in the elderly, representing the spectrum of dependency.METHODS:Multicenter project with a probabilistic population sample of 5,371 elderly residents in São Paulo, SP, Rio de Janeiro, RJ, Fortaleza, CE and Bambui, MG in 2008. A household survey was carried out and a questionnaire with 20 activities of daily living applied for the elderly to self-assess the difficulty/need for help in performing them. The responses were analyzed according to: the prevalence of some kind of difficulty/need for help for each activities of daily living, the frequency of non-response, and the grouping of activities in factor analysis.RESULTS:The personal activities (e.g., dressing) have, on average, a low prevalence of difficulty or need for help, compared to instrumental activities (e.g., shopping), and have lower rates of non- response. In factor analysis it was possible to identify three factors grouping the activities of daily living: one relative to mobility (e.g., walking 100 m), another for personal needs (e.g., bathing) and one relative to what someone else can do for the elderly (e.g., washing clothes). The activities of daily living with the highest eigenvalues in each group were also analyzed in the light of the prevalence of reported need for help and the proportion of non response. Three activities of daily living were selected as representing the spectrum of dependency and being well understood by the elderly - getting out of bed, bathing and walking 100 m.CONCLUSIONS:With only three activities of daily living we can have a simple and reliable screening instrument capable of identifying elderly in need of help in daily life. Estimating demand for care on a daily basis is an important indicator for planning and administration of health services within the paradigm of chronic diseases and population aging.