Navegando por Palavras-chave "Equipamentos E Provisões"

Agora exibindo 1 - 2 de 2
  • Nenhuma Miniatura disponível
    Item
    Somente Metadadados
    Easy-implanter: dispositivo para colocação das unidades foliculares
    (Universidade Federal de São Paulo (UNIFESP), 2019-12-13) Buttros, Juliana Beatriz [UNIFESP]; Ferreira, Lydia Masako [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)
    Introduction: Alopecia affects many individuals worldwide and hair transplant is the only ultimate treatment. Hair transplantation surgery has dramatically improved over the past decade thanks to the emergence of new techniques of follicular unit transplantation and follicular unit excision (FUE). The popularity of FUE hair transplantation has provoked the development of more advanced devices that potentially increase the quality of the hair transplant procedure, but new implanters need to be developed to minimize injury to these delicate grafts and cost while also increasing the speed of the procedure. Objective: To develop a manual device for transplanting FUE follicular units. Methods: A novelty search was conducted in national (INPI/BR) and international (USPTO, WIPO, EPO and Google Patent Search) databases. The Design Thinking methodology, which is divided into four phases (Discover, Define, Develop, and Deliver), was used in this project. In the Discover phase, interviews and desk research were conducted; in the Define phase, the main parameters and the purpose of the device were determined; in the Develop phase, brainstorming sessions were carried out; and, in the Deliver phase, the industrial design was created. Results: The characteristics of the device were defined. The final model features all the functionality defined through Design Thinking and resulted in a manual transplanter for three follicular units with individual shot and easy sterilization. Conclusion: The Easy-Implanter, a manual device for transplanting multi follicular units, was developed.
  • Imagem de Miniatura
    Item
    Acesso aberto (Open Access)
    Eficácia e segurança da implantação de hipotermia cerebral exclusiva por meio do uso de cateter nasofaríngeo em seres humanos para o tratamento de traumatismo cranioencefálico grave - estudo de fase I
    (Universidade Federal de São Paulo (UNIFESP), 2019-11-28) Ferreira, Raphael Einsfeld Simoes [UNIFESP]; Centeno, Ricardo Silva [UNIFESP]; Paiva, Bernardo Lembo Conde de [UNIFESP]; http://lattes.cnpq.br/2407213200021772; http://lattes.cnpq.br/9709796351055284; http://lattes.cnpq.br/7930858019576181; Universidade Federal de São Paulo (UNIFESP)
    Objective: The objective was to determine whether a novel nasopharyngeal catheter could be used, as a new strategy, to cool the human brain (reduction of at least 2 °C) after traumatic brain injury, and the secondary objective was to assess the local and systemic effects of this therapeutic strategy. Methods: This was a non-randomized, interventional clinical trial that involved five patients with severe traumatic brain injury. The intervention consisted of inducing and maintaining selective brain cooling for 24h by positioning a catheter in the nasopharynx and circulating cold water inside the catheter in a closed loop arrangement. Core temperature was maintained greater than 35 °C using counter-warming strategies. Results: In all study participants, a brain temperature reduction of ≥ 2 °C was achieved. The mean brain temperature reduction from baseline was 2.5 ± 0.9°C (p = .04, 95% confidence interval). The mean systemic temperature was 37.3 ± 1.1 °C at baseline and 36.0 ± 0.8 °C during the intervention. The mean difference between the brain temperature and the systemic temperature during intervention was -1.2 ± 0.8 °C (p = .04). The intervention was well tolerated with no significant changes observed in the hemodynamic parameters. No relevant variations in intracranial pressure and transcranial Doppler were observed. The laboratory results underwent no major changes, aside from the K+ levels and blood counts. The K+ levels significantly varied (p = .04); however, the variation was within the normal range. Only one patient experienced an event of mild localized and superficial nasal discoloration, which was re-evaluated on the seventh day and indicated complete recovery. Conclusion: The results suggest that our non-invasive method for selective brain cooling, using a novel nasopharyngeal catheter, was effective and safe for use in humans.