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- ItemSomente MetadadadosCurrent advances in targeted therapies for metastatic gastric cancer: improving patient care(Future medicine ltd, 2016) Aguiar, Pedro Nazareth, Jr. [UNIFESP]; Muniz, Thiago Pimentel [UNIFESP]; Miranda, Raelson Rodrigues [UNIFESP]; Tadokoro, Hakaru [UNIFESP]; Forones, Nora Manoukian [UNIFESP]; Monteiro, Ines-de-Paula; Castelo-Branco, Pedro; Janjigian, Yelena Y.; de Mello, Ramon AndradeIn this article, we review the literature on the current advances in targeted therapies for metastatic gastric cancer aimed at improving patient care. We conclude that the key to guiding targeted therapy is individual biomarkers, which are not completely elucidated. HER2 overexpression is the only predictive biomarker currently in use. Furthermore, it is necessary to understand that gastric tumors are heterogeneous
- ItemAcesso aberto (Open Access)Influence of the expression of inflammatory markers on kidney after fetal programming in an experimental model of renal failure(Czech Acad Sci, Inst Entomology, 2016) Pereira Junior, Carlos Donizete; de Oliveira Guimaraes, Camila Souza; Souza da Silva, Aline Cristina; Aquiles Rodrigues, Aldo Rogelis; da Gloria, Maria Aparecida [UNIFESP]; Antunes Teixeira, Vicente de Paula; Saraiva Camara, Niels Olsen [UNIFESP]; Rocha, Lenaldo Branco; dos Reis, Marlene Antonia; Machado, Juliana Reis; Rocha, Laura Penna; Helmo, Fernanda Rodrigues; Miranda Correa, Rosana RosaObjective. To evaluate the expression of inflammatory markers in experimental renal failure after fetal programming. Methods. The offspring aged two and fivemonths were divided into four groups: CC (control dams, control offspring)