Navegando por Palavras-chave "Endarterectomy"

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    Immediate versus delayed treatment for recently symptomatic carotid artery stenosis
    (Hindawi Publishing Corp, 2016) Vasconcelos, Vladimir [UNIFESP]; Cassola, Nicolle [UNIFESP]; da Silva, Edina M. K.; Baptista-Silva, Jose C. C. [UNIFESP]
    Background The timing of surgery for recently symptomatic carotid artery stenosis remains controversial. Early cerebral revascularization may prevent a disabling or fatal ischemic recurrence, but it may also increase the risk of hemorrhagic transformation, or of dislodging a thrombus. This review examined the randomized controlled evidence that addressed whether the increased risk of recurrent events outweighed the increased benefit of an earlier intervention. Objectives To assess the risks and benefits of performing very early cerebral revascularization (within two days) compared with delayed treatment (after two days) for people with recently symptomatic carotid artery stenosis. Search methods We searched the Cochrane Stroke Group Trials Register in January 2016, the Cochrane Central Register of Controlled Trials (CENTRAL
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    Intervenção precoce ou tardia para pacientes recentemente sintomáticos com estenose de carótida: revisão sistemática Cochrane
    (Universidade Federal de São Paulo (UNIFESP), 2016-12-31) Vasconcelos, Vladimir Tonello de [UNIFESP]; Silva, José Carlos Costa Baptista da [UNIFESP]; http://lattes.cnpq.br/7216436712130915; http://lattes.cnpq.br/7031191726790609; Universidade Federal de São Paulo (UNIFESP)
    Objectives: To assess the risks and benefits of performing very early cerebral revascularization (within two days) compared with delayed treatment (after two days) for people with recently symptomatic carotid artery stenosis. Methods: We searched the Cochrane Stroke Group Trials Register in January 2016, the Cochrane Central Register of Controlled Trials (CENTRAL; The Cochrane Library 2016, Issue 1), MEDLINE (1948 to 26 January 2016), EMBASE (1974 to 26 January 2016), LILACS (1982 to 26 January 2016), and trial registers (from inception to 26 January 2016). We contacted colleagues and pharmaceutical companies to identify further studies and unpublished trials. All completed, truly randomized trials (RCT) that compared very early cerebral revascularization (within two days) with delayed treatment (after two days) for people with recently symptomatic carotid artery stenosis. We independently selected trials for inclusion according to the above criteria, assessed risk of bias for each trial, and performed data extraction. We utilized an intention-to-treat analysis strategy. Results: We identified one single RCT that involved 40 participants, and addressed the timing of surgery for people with recently symptomatic carotid artery stenosis. It compared very early surgery with surgery performed after 14 days of the last symptomatic event. The overall quality of the evidence was very low, due to the small number of participants from only one trial, and missing outcome data. We found no statistically significant difference between the effects of very early or delayed surgery in reducing the combined risk of stroke and death within 30 days of surgery (risk ratio (RR) 3.32; confidence interval (CI) 0.38 to 29.23; very low-quality evidence), or the combined risk of perioperative death and stroke (RR 0.47; CI 0.14 to 1.58; very lowquality evidence). To date, no results are available to confirm the optimal timing for surgery. Conclusions: There is currently no high-quality evidence available to support either very early or delayed cerebral revascularization after a recent ischemic stroke. Hence, further randomized trials to identify which patients should undergo very urgent revascularization are needed. Future studies should stratify participants by age group, sex, grade of ischemia, and degree of stenosis.
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    Reoperação de tromboendarterectomia pulmonar em recidiva de tromboembolismo pulmonar crônico hipertensivo
    (Sociedade Brasileira de Pneumologia e Tisiologia, 2009-01-01) Gomes, Walter José [UNIFESP]; Imaeda, Carlos Jogi [UNIFESP]; Perfeito, João Aléssio Juliano [UNIFESP]; Sarmento, Petrúcio Abrantes [UNIFESP]; Souza, Rodrigo Caetano [UNIFESP]; Forte, Vicente [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)
    Pulmonary thromboendarterectomy has been established as the standard method for the treatment of chronic thromboembolic pulmonary hypertension, with excellent results. However, repeat pulmonary thromboendarterectomy due to recurrence of pulmonary embolism has never been reported in the Brazilian literature. Its safety and effectiveness remain obscure. We report the case of a patient presenting recurrence of chronic thromboembolic pulmonary hypertension five years after the first pulmonary thromboendarterectomy and requiring a second operation for resolution of the symptoms.