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- ItemAcesso aberto (Open Access)Avaliação de uma estratégia de identificação de portadores de hepatite c em unidades ambulatoriais e de pronto-atendimento(Universidade Federal de São Paulo (UNIFESP), 2018-06-06) Gardona, Rodrigo Galvao Bueno [UNIFESP]; Ferraz, Maria Lucia Cardoso Gomes [UNIFESP]; http://lattes.cnpq.br/1870810357457710; http://lattes.cnpq.br/5664463566153721; Universidade Federal de São Paulo (UNIFESP)Introduction: Hepatitis C is a viral infection that affects the liver, representing a serious public health problem. Over the years, a reduction in the prevalence of infection has been observed worldwide, due to the deaths caused by complications of the disease, in people who have become infected in the past. The greatest challenge today is the identification of infected individuals who are not yet evaluated for treatment. As the highest prevalence rate is observed in people of more advanced age, the search should be done primarily in this population. In addition to the age group as a criterion, the place of the search may also be useful as an identification strategy. Objective: To identify the prevalence of HCV infection in patients over 45 years old in the emergency room and outpatient clinics of a tertiary hospital and to evaluate the sociodemographic, clinical and laboratory characteristics of the patients evaluated. Method: This was a crosssectional, descriptive and analytical study of individuals of both genders, aged ≥45 years. The research was developed at the emergency unit and outpatient clinics at Hospital São Paulo, SP, Brazil. After compliance with the eligibility criteria and formal consent, the patients responded to a structured interview (sociodemographic and clinical questions) and were submitted to the rapid test for antiHCV (SD BIOLINE®, Alere, China). Results: 606 people of both genders (62% female and 37% male) participated in the study. The mean age was 62 years. Regarding the previous diagnostic test for HCV, 65% reported never having performed it and 18% did so at some point in their life. Four positive tests with serological confirmation (antiHCV and HCVRNA) were identified. Thus, the observed prevalence was 0.66%. All patients had identifiable risk factors: injecting drug use, sexual intercourse with antiHCV positive partner, and blood transfusion. Conclusion: Although the study has been developed in a hospital service of high complexity and in a specific age group, a low prevalence of hepatitis C was observed in the studied population. This result is in line with other studies, which have revealed a lower prevalence of hepatitis C in Brazil, in relation to that previously verified. These results must be taken into account for the adequacy of public policies to combat the disease.
- ItemSomente MetadadadosViolence and non-violence-related injuries and alcohol in women from developed and developing countries: A multi-site emergency room study(Elsevier B.V., 2015-02-01) Silva, Rosiane Lopes da [UNIFESP]; Diehl, Alessandra [UNIFESP]; Cherpitel, Cheryl J.; Figlie, Neliana B. [UNIFESP]; Universidade Federal de São Paulo (UNIFESP); Natl Alcohol Res Ctr; Publ Hlth Inst Alcohol Res Grp; CNPqThis study sought to analyze the association between alcohol consumption and the occurrence of injuries in women attending the emergency room (ER) from developing and developed countries. the sample consisted of ER data from women in 15 countries that were collected as part of two multi-site studies using similar methodologies: the Emergency Room Collaborative Alcohol Analysis Project (ERCAAP), and World Health Organization Collaborative Study on Alcohol and Injuries (WHO Study). Women ranged in age from 18 to 98 years. Those from developed,countries had higher levels of education (43% completed high-school) than women from developing countries (37%). Over half of the women from developing countries reported they had not consumed alcohol in the last 12 months (abstentious), while 2% reported drinking every day. in addition, current drinking women from developing countries reported more binge drinking episodes (33% reported 5 toll drinks and 15% reported 12 or more drinks on an occasion) compared to those from developed countries (28% and 11%, respectively). Violence-related injury was more prevalent in developing countries (18%) compared to developed countries (9%). An association between injury and the frequency of alcohol consumption in the last 12 months was observed in both developing and developed countries. Although women from developing countries who suffered violence-related injuries were more likely to demonstrate alcohol abstinence or have lower rates of daily alcohol consumption, these women drank in a more dangerous way, and violence-related injuries were more likely to occur in these women than in those living in developed countries. (C) 2014 Elsevier B.V. All rights reserved.