Navegando por Palavras-chave "ECT"

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    Neuromodulation approaches for the treatment of major depression: challenges and recommendations from a working group meeting
    (Academia Brasileira de Neurologia - ABNEURO, 2010-06-01) Brunoni, André Russowsky; Teng, Chei Tung; Corrêa, Claudio Fernandes [UNIFESP]; Imamura, Marta; Brasil-Neto, Joaquim P; Boechat, Raphael; Rosa, Moacyr Alexandro [UNIFESP]; Caramelli, Paulo; Cohen, Roni; Porto, Jose Alberto Del [UNIFESP]; Boggio, Paulo Sergio; Fregni, Felipe; University of São Paulo Department and Institute of Psychiatry; Hospital 9 de Julho Pain Center and Functional Neurosurgery; University of Paulo Department of Physical Medicine and Rehabilitation; University of Brasília Laboratory of Neurosciences and Behavior; Columbia University; Federal University of Minas Gerais Faculty of Medicine Department of Internal Medicine (Neurology Unit); Centro Brasileiro de Estimulação Magnética; Universidade Federal de São Paulo (UNIFESP); University Mackenzie; Spaulding Rehabilitation Hospital Laboratory of Neuromodulation; Harvard Medical School; Berenson-Allen Center for Noninvasive Brain Stimulation; Harvard Medical School Beth Israel Deaconess Medical Center
    The use of neuromodulation as a treatment for major depressive disorder (MDD) has recently attracted renewed interest due to development of other non-pharmacological therapies besides electroconvulsive therapy (ECT) such as transcranial magnetic stimulation (TMS), transcranial direct current stimulation (tDCS), deep brain stimulation (DBS), and vagus nerve stimulation (VNS). METHOD: We convened a working group of researchers to discuss the updates and key challenges of neuromodulation use for the treatment of MDD. RESULTS: The state-of-art of neuromodulation techniques was reviewed and discussed in four sections: [1] epidemiology and pathophysiology of MDD; [2] a comprehensive overview of the neuromodulation techniques; [3] using neuromodulation techniques in MDD associated with non-psychiatric conditions; [4] the main challenges of neuromodulation research and alternatives to overcome them. DISCUSSION: ECT is the first-line treatment for severe depression. TMS and tDCS are strategies with a relative benign profile of side effects; however, while TMS effects are comparable to antidepressant drugs for treating MDD; further research is needed to establish the role of tDCS. DBS and VNS are invasive strategies with a possible role in treatment-resistant depression. In summary, MDD is a chronic and incapacitating condition with a high prevalence; therefore clinicians should consider all the treatment options including invasive and non-invasive neuromodulation approaches.
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    Simultaneous Low (1 Hz)- and High (10 Hz)-Frequency Bilateral Transcranial Magnetic Stimulation in a Patient With Severe Depression and Crohn Disease
    (Lippincott Williams & Wilkins, 2012-09-01) Rosa, Moacyr Alexandro [UNIFESP]; Andrade, Marco Aurelio [UNIFESP]; Abdo, Guilherme Lozi [UNIFESP]; Rosa, Marina Odebrecht; Universidade Federal de São Paulo (UNIFESP); IPAN
    We present a case report in which electroconvulsive therapy had a good effect for the treatment of depression in association with Crohn disease, but adverse effects limited its use. Repetitive transcranial magnetic stimulation was tried both in a conventional way (high frequency over the left dorsolateral prefrontal cortex) and in a bilateral sequential way (high frequency in the same region followed in the same session by low frequency on the right side). Finally, bilateral simultaneous stimulation (high frequency over the left and low frequency over the right side) was tried and resulted in a response similar to that of electroconvulsive therapy.