Navegando por Palavras-chave "Dystonic disorders"

Agora exibindo 1 - 2 de 2
  • Imagem de Miniatura
    Item
    Acesso aberto (Open Access)
    Comparison of clinical characteristics of patients with adductor laryngeal dystonia in the focal and segmental types
    (Assoc Brasileira Otorrinolaringologia & Cirurgia Cervicofacial, 2011-07-01) Korn, Gustavo Polacow [UNIFESP]; Moraes, Miriam; Pereira Vilanova, Luiz Celso [UNIFESP]; Moraes, Bruno Teixeira de [UNIFESP]; Madazio, Glaucya; Padovani, Marina Martins Pereira; De Biase, Noemi Grigoletto [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)
    Dystonia is a central motor processing neurological disorder characterized by abnormal, often action-induced, involuntary movements or uncontrolled spasms.Aim: To compare patients with the diagnoses of focal and segmental adductor laryngeal dystonia at the Neurolarynx Outpatient Clinic of the Federal University of Sao Paulo.Materials and methods: A clinical retrospective study of data collected from patient registries from 2003 to 2009.Results: Of 34 patients, 25 presented focal dystonia and 9 presented segmental dystonia. There were 30 females (88.2%) and 4 males (11.8%). A relation with a traumatic event was reported in 11 cases (32.4%). Vocal tremor was observed in 21 patients (61.8%). The mean age at onset, the age at diagnosis, and time between the onset and the diagnosis were respectively 55, 61.3 and 6.3 years. There was no statistical difference between patients with focal laryngeal adductor dystonia and segmental dystonia in the study data.Conclusion: There were no statistical differences among patients with focal adductor laryngeal dystonia and segmental dystonia relating to age of onset, age of diagnosis, gender, time between onset and diagnosis, presence of associated tremor, and relation to trauma.
  • Imagem de Miniatura
    Item
    Acesso aberto (Open Access)
    Influência da toxina botulínica tipo A na função lacrimal de pacientes com distonias faciais
    (Conselho Brasileiro de Oftalmologia, 2010-10-01) Oliveira, Fernanda Castro de [UNIFESP]; Oliveira, Gustavo Castro de; Cariello, Angelino Julio [UNIFESP]; Felberg, Sergio; Osaki, Midori Hentona [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)
    PURPOSE: To analyze the influence of botulinum toxin on the lacrimal function of patients with facial dystonias. METHODS: Patients with the diagnosis of hemifacial spasm or benign essential blepharospasm were evaluated and invited to answer the Ocular Surface Index Disease (OSID) questionnaire. All patients underwent Schirmer I and basal tests; break-up time (BUT) test and lacrimal clearance evaluation. On the following day, the patients were treated with botulinum toxin. The Ocular Surface Index Disease questionnaire and all the initial tests were reapplied 30 days after the treatment by the same examiner. RESULTS: Twenty-six patients were enrolled in this study, 15 (57.7%) with hemifacial spasm and 11 (42.3%) with benign essential blepharospasm. The mean age of patients with hemifacial spasm was 70.9 ± 13.3 years and the male:female ratio was 1:1.5. In the group of patients with benign essential blepharospasm, the mean age was 68.9 ± 8.4 years with a female preponderance (90.0%). After the treatment, the Ocular Surface Index Disease score, Schirmer I and basal tests score decreased in both groups. The mean of Break-up time test increased significantly in both groups. The lacrimal clearance evaluation showed a greater number of eyes that achieved a complete drainage of the tears after the treatment in both groups. CONCLUSION: The treatment with botulinum toxin improved dry eye symptoms in patients with facial dystonia. Despite of the aqueous portion of tear have decreased, blink modifications improved the tear stability and drainage.