Navegando por Palavras-chave "Disco óptico"
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- ItemAcesso aberto (Open Access)Correlação da espessura das células ganglionares da retina macular e a espessura da camada de fibras nervosas da retina superior e inferior do disco óptico em pacientes com glaucoma inicial(Universidade Federal de São Paulo, 2022) Coelho, Matheus Oliveira da Rocha [UNIFESP]; Barretto, Gabriel Baldon [UNIFESP]; Silva, Willian Jorge Pires da [UNIFESP]; Tavares, Ivan Maynart [UNIFESP]; http://lattes.cnpq.br/9220084935194992; http://lattes.cnpq.br/1757065771152066; http://lattes.cnpq.br/2239180444011832; http://lattes.cnpq.br/4910084186347216Objetivo: Analisar a correlação entre a espessura de células ganglionares da retina na mácula e a espessura da camada de fibras nervosas da retina na região peripapilar superior e inferior. Métodos: Analisar os cortes obtidos por meio da Tomografia de Coerência Óptica de 26 pacientes com suspeita de glaucoma ou glaucoma inicial. Resultados: Os pacientes com uma diminuição da espessura média da camada de fibras nervosas apresentam concomitantemente um afinamento da espessura de células ganglionares da retina macular. Conclusão: A perda de fibras nervosas na região peripapilar superior e inferior se acompanha de um afinamento importante na espessura macular, sendo esta uma análise importante para o diagnóstico precoce de glaucoma.
- ItemAcesso aberto (Open Access)Different presentations of intraretinal fluid collections in optic disc pits: OCT study of 3 cases(Conselho Brasileiro de Oftalmologia, 2006-10-01) Brasil, Oswaldo Ferreira Moura [UNIFESP]; Brasil, Maria Vitoria Oliveira Moura [UNIFESP]; Brasil, Oswaldo Moura; Universidade Federal de São Paulo (UNIFESP); IBOL Setor de Retina e VítreoThe congenital optic disc pit is a rare anomaly that can lead to major visual impairment associated with subretinal fluid accumulation. The authors describe the optical coherence tomography study of three cases of untreated congenital optic disc pits with different levels of visual impairment and its different presentations of intraretinal fluid collections.
- ItemAcesso aberto (Open Access)Factors affecting the variability of the Heidelberg Retina Tomograph III measurements in newly diagnosed glaucoma patients(Conselho Brasileiro de Oftalmologia, 2010-08-01) Prata, Tiago dos Santos [UNIFESP]; Meira-Freitas, Daniel [UNIFESP]; Lima, Verônica Castro [UNIFESP]; Guedes, Lia Manis [UNIFESP]; Magalhães, Fernanda Pedreira [UNIFESP]; Paranhos Junior, Augusto [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)PURPOSE: To determine factors associated with the test-retest variability of optic nerve head (ONH) topography measurements with confocal scanning laser ophthalmoscopy (CSLO) in newly diagnosed glaucomatous patients. METHODS: Consecutive patients with newly diagnosed primary open-angle glaucoma were prospectively enrolled. Patients presenting with any ocular disease other than glaucoma were excluded. All patients underwent CSLO using the Heidelberg Retina Tomograph III (HRT-III) in one randomly selected eye (three consecutive scans; performed by the same examiner). For each Heidelberg Retina Tomograph III parameter, repeatability was assessed using within subject standard deviation (Sw) and coefficient of variation (CVw), repeatability coefficient (RC) and intraclass correlation coefficient (ICC). Scatter plots and regression lines were constructed to identify which factors influenced test-retest measurement variability. RESULTS: A total of 32 patients were included (mean age, 65.4 ± 13.8 years). Most patients were female (65%) and white (50%). Among all Heidelberg Retina Tomograph III parameters evaluated, rim area and mean cup depth had the best measurement repeatability. Vertical cup-to-disc ratio (CDR, as determined by optic disc stereophotograph examination) was significantly associated (R²=0.21, p<0.01) with test-retest measurement variability. Eyes with larger CDR showed less variable measurements. Other factors, including age, disc area, central corneal thickness and intraocular pressure were not significant (p>0.14). CONCLUSION: Heidelberg Retina Tomograph III showed good test-retest repeatability for all ONH topographic measurements, mainly for rim area and mean cup depth. Test-retest repeatability seemed to improve with increasing CDR. These findings suggest that HRT-III topographic measurements should be cautiously interpreted when evaluating longitudinally glaucoma patients with early structural damage (small CDR).
- ItemAcesso aberto (Open Access)Melanocitoma do nervo óptico(Sociedade Brasileira de Oftalmologia, 2008-12-01) Gouveia, Enéias Bezerra; Morales, Maira Saad De Ávila [UNIFESP]; Centro Médico Avimed; Universidade Federal de São Paulo (UNIFESP)Melanocytoma of the optic disc is a well known variant of melanocytic nevus that usually occurs as a deeply pigmented lesion on the head of the optic disc. Historically, this tumor has often been confused with malignant melanoma. Histopathologically, it is composed of deeply pigmented round oval cells with abundant cytoplasm and small, round, bland nuclei. Melanocytomas is a benign, stationary tumors, with almost no propensity to undergo malignant transformation. Most cases that occur on the optic disc are visually asymptomatic, but they can cause an afferent pupillary and visual field defects. Importantly, it can exhibit malignant transformation into melanoma in 1 to 2% of the cases. The affected patients should have periodic follow up.
- ItemAcesso aberto (Open Access)Simulated cup/disc ratio: a tool for ophthalmologists(Conselho Brasileiro de Oftalmologia, 2010-08-01) Barbosa, Carolina Pelegrini [UNIFESP]; Angelini, Pedro Felipe; Schor, Paulo [UNIFESP]; Paranhos Junior, Augusto [UNIFESP]; Universidade Federal de São Paulo (UNIFESP); Universidade de São Paulo (USP)PURPOSE: To evaluate and compare the observers' ability to measure simulations of cup/disc ratios (CDR) as concentric and non-concentric circles. METHODS: In a prospective, random, and masked setting, 43 images representing the CDR spectrum from 0.2 to 0.9 for vertical and horizontal CDR measurements were developed and presented on a computer screen to 171 participants. RESULTS: There were satisfactory agreements according to the kappa coefficient (0.755 and 0.730 for horizontal and vertical cup disc ratios, respectively) and Lin's concordance correlation (R=0.88 and R=0.86 for horizontal and vertical measurements, respectively). However, very poor agreement was found for intermediate CDR values. The worst agreement occurred when the CDR was between 0.4 and 0.6 for both the horizontal and vertical values. The kappa coefficient was 0.37 and 0.39 for 0.4 CDR (horizontal and vertical, respectively), 0.39 and 0.38 for 0.5 CDR (horizontal and vertical, respectively) and 0.45 and 0.41 for 0.6 CDR (horizontal and vertical, respectively). CONCLUSION: Despite a good general agreement between the gold standard and the participants' responses, the absolute agreement for intermediate CDR values was very poor for both horizontal and vertical values.