Navegando por Palavras-chave "Custo de manufatura"

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    Avaliação econômica da obtenção de extrato de bagaço de maracujá: uma comparação entre as técnicas de extração com líquido pressurizado e líquido pressurizado assistida por ultrassom
    (Universidade Federal de São Paulo, 2021-07-15) Ferreira, Wilson Santos [UNIFESP]; Veggi, Priscilla Carvalho [UNIFESP]; Viganó, Juliane; http://lattes.cnpq.br/6020226876173532; http://lattes.cnpq.br/4337428740305589; http://lattes.cnpq.br/8882671734599669
    Natural products and plant extracts have been widely used in recent years and have a growing and relevant importance in the pharmaceutical, food, and cosmetics sectors, due to the bioactive properties of their compounds. The development of extraction technologies and processes are fundamental to the growth of this sector, especially the extraction with supercritical fluids (SFE), with pressurized liquid (PLE), and ultrasound-assisted extraction (US). In the process design step, the use of simulators is one of the most important steps due to the software's ability to predict the behavior of processes, providing information for the project’s economic feasibility analysis and scale-up scenarios. In this context, this work presents the economic feasibility study of two different extraction processes for obtaining a piceatannol-rich extract from yellow passion fruit bagasse, namely, process A (supercritical fluid extraction + pressurized liquid extraction – SFE+PLE) at 65 and 75 ºC and process B (SFE+PLE assisted by ultrasound – SFE+PLE-US) at 65 ºC and 440 W. The SuperPro Designer® software was employed to estimate the manufacturing cost (COM), productivity, and economic return rates, which were calculated for each overall extraction curve (5 to 300 min) and different scales (50, 200, and 500 L). Scale-up increased productivity and reduced COM, improving the economic return rates. Process A proved to be economically viable, while process B was unfeasible at a minimum acceptable rate of return (MARR) of 20%. The lowest COM and the best economic return were obtained with process A at 75 ºC, 500 L scale, and processing time of 90 min. A sensitivity study was carried out and indicated that it is possible to sell the extract at a price below the market price, representing a competitive differential to implement this process. It is noteworthy that up to now, the economic feasibility of PLE-US on a large scale had not yet been performed, so this work represents a starting point for studies of PLE-US hybridization at large scales.