Navegando por Palavras-chave "Citrus aurantium"

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    The antimicrobial effects of Citrus limonum and Citrus aurantium essential oils on multi-species biofilms
    (Sociedade Brasileira de Pesquisa Odontológica - SBPqO, 2014-01-01) Oliveira, Sarah Almeida Coelho; Zambrana, Jéssica Rabelo Mina; Di Iorio, Fernanda Bispo Reis; Pereira, Cristiane Aparecida; Jorge, Antonio Olavo Cardoso; Universidade Estadual Paulista (UNESP); Universidade Federal de São Paulo (UNIFESP)
    The aim of this study was to evaluate the effects of Citrus limonum and Citrus aurantium essential oils (EOs) compared to 0.2% chlorhexidine (CHX) and 1% sodium hypochlorite (NaOCl) on multi-species biofilms formed by Candida albicans, Enterococcus faecalis and Escherichia coli. The biofilms were grown in acrylic disks immersed in broth, inoculated with microbial suspension (106 cells/mL) and incubated at 37°C / 48 h. After the biofilms were formed, they were exposed for 5 minutes to the solutions (n = 10): C. aurantium EO, C. limonum EO, 0.2% CHX, 1% NaOCl or sterile saline solution [0.9% sodium chloride (NaCl)]. Next, the discs were placed in sterile 0.9% NaCl and sonicated to disperse the biofilms. Tenfold serial dilutions were performed and the aliquots were seeded onto selective agar and incubated at 37°C / 48 h. Next, the number of colony-forming units per milliliter was counted and analyzed statistically (Tukey test, p ≤ 0.05). C. aurantium EO and NaOCl inhibited the growth of all microorganisms in multi-species biofilms. C. limonum EO promoted a 100% reduction of C. albicans and E. coli, and 49.3% of E. faecalis. CHX was less effective against C. albicans and E. coli, yielding a reduction of 68.8% and 86.7%, respectively. However, the reduction of E. faecalis using CHX (81.7%) was greater than that obtained using C. limonum EO. Both Citrus limonum and Citrus aurantium EOs are effective in controlling multi-species biofilms; the microbial reductions achieved by EOs were not only similar to those of NaOCl, but even higher than those achieved by CHX, in some cases.
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    Behavioral effects of essential oil of Citrus aurantium L. inhalation in rats
    (Sociedade Brasileira de Farmacognosia, 2008-12-01) Leite, Mariana P. [UNIFESP]; Fassin Junior, Jaime [UNIFESP]; Baziloni, Eliane Maria de Freitas [UNIFESP]; Almeida, Reinaldo Nobrega de; Mattei, Rita [UNIFESP]; Leite, Jose Roberto [UNIFESP]; Universidade Federal de São Paulo (UNIFESP); Universidade Federal da Paraíba Laboratório de Tecnologia Farmacêutica
    The orange essential oil (OEO) and its components obtained from Citrus aurantium L. (Rutaceae) has been attracting interest due to its sedative and relaxing actions. In the present study, rats previously exposed to OEO at the concentrations of 1.0%; 2.5% and 5.0%, w/w, by inhalation during 7 minutes in acrylic boxes were evaluated in two anxiety models: elevated plus maze (EPM) and open-field. The OEO at the concentration of 2.5% increased both the time of the animals in the open arms of the EPM and the time of active social interaction in the open-field being longer than that of the diazepam group (1.5 mg/kg i.p). In conclusion, the decrease in the level of emotionality of the animals observed in the two experimental models suggests a possible central action, which is in agreement with the phytochemical profile of the oil under study, since it showed the presence of limonene (96.24%) and mircene (2.24%), components with a well-known depressant activity on the central nervous system.