Navegando por Palavras-chave "Caffeine intake"

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    The association between caffeine consumption and objective sleep variables is dependent on ADORA2A c.1083T>C genotypes
    (Elsevier Science Bv, 2017) Nunes, Rafael Almeida [UNIFESP]; Mazzotti, Diego Robles [UNIFESP]; Hirotsu, Camila [UNIFESP]; Andersen, Monica L. [UNIFESP]; Tufik, Sergio [UNIFESP]; Bittencourt, Lia [UNIFESP]
    Objective: To verify the association between c.1083T>C polymorphism in the adenosine receptor A2A gene (ADORA2A) and objective sleep, as well as the correlation between caffeine consumption, sleep parameters, and electroencephalographic spectral power in a large, population-based sample from Sao Paulo, Brazil. Methods: This study was conducted in participants of the Sao Paulo Epidemiologic Sleep Study (EPISONO), a large, population-based survey consisting of a representative sample of the inhabitants of the city from Sao Paulo, Brazil, according to sex, age (20-80 years), and socioeconomic status in the year 2007. Questionnaires, polysomnography, spectral analysis of sleep electroencephalogram, and c.1083T>C polymorphism genotyping were performed in this study. Results: We found that caffeine consumption was positively correlated with sleep latency and a spectral power, as well as negatively correlated with percentage of N3 stage and delta spectral power in this stage. However, this association was identified only in T allele carriers and not in CC genotype. Conclusion: Our data support an important aspect of this polymorphism in ADORA2A gene, showing that the variant affects the association between caffeine consumption and objective sleep parameters in a large population-based cohort. (C) 2016 Elsevier B.V. All rights reserved.
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    Efeitos da ingestão aguda de cafeína sobre o perfil inflamatório, metabolismo lipídico e parâmetros psicobiológicos, em resposta ao exercício físico intervalado de alta intensidade
    (Universidade Federal de São Paulo (UNIFESP), 2019-10-31) Campos, Raquel Rocha de [UNIFESP]; Santos, Ronaldo Vagner Thomatieli dos [UNIFESP]; http://buscatextual.cnpq.br/buscatextual/visualizacv.do?id=K4776000A2; http://buscatextual.cnpq.br/buscatextual/visualizacv.do?id=K8120153E6; Universidade Federal de São Paulo (UNIFESP)
    Caffeine is one of the most commonly consumed psychoactive substances nowadays, especially by those who exercise on a regular basis. However, with the search for weight loss and performance improvement, high intensity interval training became their new way of practicing exercise. This project aimed to investigate the effects of acute caffeine intake on decaffeinated coffee (6mg/kg/weight in 100 ml of water with 5 g of decaffeinated ground coffee) on pre & post-workout, and in the recovery phase after a 60 min high intensity interval training on immonutrition aspect (interleukin 6,10,and tumor necrosis factor alpha), lipid metabolism (free fatty acids, triglycerides, glycerol and glucose) and psychobiological parameters (state-trait anxiety inventory, brunel, subjective exercise experience scale, visual pain scale and borg scale), which anxiety is also related to a concentration of neurotransmitters such as glutamate and serotonin dosage. The sample consisted of 10 healthy young male and female volunteers randomly assigned to two different conditions: (1) high intensity interval training with placebo and (2) high intensity interval training with caffeine. All variables were analyzed at pre & post-workout, and during recovery for both conditions. The treatment administration followed a randomized, crossover and double-blind design study. The statistical analysis used was performed through general linear model with the appropriate corrections and a significance level of p≤0,05. Caffeine did not altered mood and anxiety, not did it show changes in neurotransmitters after training and recovery phase. Therefore, this study showed that caffeine is indeed capable of slightly weaken inflammatory effects caused by high intensity interval training and also improve the release of fatty acids after exercising. Thus providing a training modality in which caffeine may be an ergogenic and anti-inflammatory feature.
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    Effects of the Adenosine Deaminase Polymorphism and Caffeine Intake on Sleep Parameters in a Large Population Sample
    (Amer Acad Sleep Medicine, 2011-03-01) Mazzotti, Diego Robles [UNIFESP]; Guindalini, Camila [UNIFESP]; Pellegrino, Renata [UNIFESP]; Barrueco, Karina Fonseca [UNIFESP]; Santos-Silva, Rogerio [UNIFESP]; Bittencourt, Lia Rita Azeredo [UNIFESP]; Tufik, Sergio [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)
    Study Objectives: To evaluate the association between the adenosine deaminase polymorphism, sleep architecture, and caffeine consumption.Design: Genetic association study.Setting: NAPatients or Participants: 958 participants who underwent polysomnography and genotyping.Interventions: NAMeasurements and Results: Individuals carrying the A allele who consumed caffeine in the day prior to polysomnography demonstrated higher sleep efficiency and REM sleep percentage, after adjustment for potential confounders. No effect was observed in the absence of caffeine.Conclusions: Our data support the role of the ADA G22A polymorphism in sleep, and demonstrate for the first time that caffeine may act as a modulator of its functional effects.