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    Avaliação da reprodutibilidade e da validade de critério das versões em português do Brasil dos questionários: European Organization for Research and Treatment of Cancer Quality of Life Core Questionnaire (EORTC QLQ-C30) associado ao Quality of Life Questionnaire Lung Cancer (QLQ-LC13) e Functional Assessment of Cancer Therapy-Lung (FACT-L) com o FACT-L Symptom Index (FLSI)
    (Universidade Federal de São Paulo (UNIFESP), 2010-02-24) Pereira, Juliana Franceschini [UNIFESP]; Santoro, Ilka Lopes [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)
    Introduction: The assessment of quality of life in patients with lung cancer has become one of the main goal in current clinical trials. For lung cancer patients, the most common quality of life tools available are the European Organization for Research and Treatment of Cancer Quality of Life Core Questionnaire (EORTC QLQ-C30) + Quality of Life Questionnaire Lung Cancer (QLQ-LC13) and the Functional Assessment of Cancer Therapy-Lung (FACT-L). Despite the amount of data available about these questionnaires, there are no data on its performance in the Brazilian patients with lung cancer. The purpose of this study was to assess the reliability and the criterion validity of the Brazilian version of the EORTC QLQ-C30 + QLQ-LC13 and the FACT-L with the FACT-L Symptom Index (FLSI) questionnaires. Methods: The EORTC QLQ-C30 + QLQ-LC13 and FACT-L with the FLSI questionnaires were administered prospectively to 50 consecutive-stable-lung cancer outpatients. For the reliability study, the questionnaires were applied at baseline and 2 weeks. The criterion validity of the questionnaires was examined through correlation with clinical and functional parameters, Karnofsky scale and similar domains of SF-36. Results: The intraclass correlation coefficient between test and retest ranged from 0,64 to 1,0 for the QLQ-C30 and from 0,64 to 0,95 for the QLQ-LC13. For the FACT-L, it ranged from 0,79 to 0,96 and for the FLSI, it was 0,87. There was no correlation between these questionnaires dimensions and clinical or functional parameters. Several scores of the study questionnaires correlated well with Karnofsky scale. The EORTC QLQ-C30 + QLQ-LC13, and the FACT-L with the FLSI scales showed good correlation among their similar dimensions, moreover they had as well good correlation with the homologous SF-36 domains. Conclusions: The Brazilian version of the questionnaires EORTC QLQ-C30 + QLQ-LC13 and FACT-L with FLSI have good reliability, are simple, and have good correlation with the SF-36. These instruments can now be used to properly evaluate the quality of life of the Brazilian lung cancer patients.