Navegando por Palavras-chave "Câncer de colo uterino"
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- ItemAcesso aberto (Open Access)Avaliação das ações de rastreamento do câncer de colo uterino no Parque Indígena do Xingu(Universidade Federal de São Paulo (UNIFESP), 2019-03-28) Scopin, Ana Carolina Carvalho [UNIFESP]; Speck, Neila Maria de Gois [UNIFESP]; Tso, Fernanda Kesselring [UNIFESP]; http://lattes.cnpq.br/4640267129189904; http://lattes.cnpq.br/8169544398769371; http://lattes.cnpq.br/3181443805404423; São Paulo; Universidade Federal de São Paulo (UNIFESP)Introduction: There are few epidemiological studies on Human Papillomavirus (HPV) infection and cervical cancer in indigenous populations. Because it is a specific population with habits and rituals of its own, HPV infection and its onco genesis could not present the same evolution in Relation to the populations commonly studied. Through the data over time analysis, it was possible to determine the most appropriate form of follow-up, aiming the diagnosis of cervical lesions, reduction of care costs and lower morbidity. Objective: To evaluate 13 years of cervical cancer screening actions and assistance in the Xingu Indigenous Park, through cytological alterations analysis, correlating age and DNA-HPV test. Methods: This is an observational, transversal and retrospective study conducted by data analysis of screening and control actions of uterine cervical cancer in the scope of the Xingu project of the Universidade Federal de São Paulo (UNIFESP). The population studied consiste do find igenous, sexually active women, aged 11 years or older, belonging to sixteen ethnic groups residing in the middle, lower and east Xingu regions. The study was developed with the analysis of the result sobtained by convencional cervical screening test (Pap smear). Results: The population coverage of cytological examination in the period averaged 89.4%. In all actions, there was a higher percentage of normal cytological results. In 2005 and 2010 years, occurred the largest number of cytological alterations, with high-grade squamous intra epithelial lesion (HSIL) and low-grade squamous intraepithelial lesion (LSIL) respectively. Only 3 cases of cervical cancer were documented over the 13 years of follow-up. The HPV positivite rate was 24.5% and latency 22.9%. Conclusion: It was observed that the high coverage of the population was valuable in maintaining the quality of screening because of the large number of normal exams and rare cases of cancer compared to the national incidence. The extremes of the ages showed a higher percentage of LSIL and HSIL respectively. The basic DNA-HPV test, without genotyping, confirmed a higher percentage of positivity in those who had HSIL.
- ItemAcesso aberto (Open Access)Ressonância magnética para avaliação dos limites dos campos clássicos de radioterapia em pacientes portadoras de neoplasia maligna de colo uterino(Colégio Brasileiro de Radiologia e Diagnóstico por Imagem, 2010-06-01) Freire, Geison Moreira [UNIFESP]; Dias, Rodrigo Souza [UNIFESP]; Giordani, Adelmo José [UNIFESP]; Ribalta, Julisa Chamorro Lascasas [UNIFESP]; Segreto, Helena Regina Comodo [UNIFESP]; Segreto, Roberto Araujo [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)OBJECTIVE: To evaluate, by means of magnetic resonance imaging, the standardized field borders in radiotherapy for malignant neoplasm of uterine cervix, and to determine the role of this method in the reduction of possible planning errors related to the conventional technique. MATERIALS AND METHODS: Magnetic resonance imaging studies for planning of treatment of 51 patients with uterine cervix cancer were retrospectively analyzed. The parameters assessed were the anterior and posterior field borders on sagittal section. RESULTS: The anterior field border was inappropriate in 20 (39.2%) patients and geographic miss was observed in 37.3% of cases in the posterior border. The inappropriateness of both field borders did not correlate with clinical parameters such as patients' age, tumor staging, histological type and degree. CONCLUSION: The evaluation of standardized field borders with the use of magnetic resonance imaging has demonstrated high indices of inappropriateness of the lateral field borders, as well as the relevant role of magnetic resonance imaging in the radiotherapy planning for patients with uterine cervix cancer with a view to reduce the occurrence of geographic miss of the target volume.