Navegando por Palavras-chave "Atrofia óptica"
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- ItemSomente MetadadadosAção da mitomicina C nas estruturas intrasculares de olhos de coelhos(Universidade Federal de São Paulo (UNIFESP), 1994) Mitre, Jorge [UNIFESP]; Farah, Michel Eid [UNIFESP]
- ItemAcesso aberto (Open Access)Retinal nerve fiber layer atrophy as relevant feature for diffuse unilateral subacute neuroretinitis (DUSN): case series(Conselho Brasileiro de Oftalmologia, 2010-04-01) Casella, Antonio Marcelo Barbante; Farah, Michel Eid [UNIFESP]; Souza, Eduardo Cunha de [UNIFESP]; Belfort, Rubens Junior [UNIFESP]; Oguido, Ana Paula Miyagusko Taba; State University of Londrina; Universidade Federal de São Paulo (UNIFESP); UELPURPOSE: To report the findings of optical coherence tomography (OCT) in three cases of diffuse unilateral subacute neuroretinitis (DUSN). METHODS: Three young patients with confirmed diagnosis of diffuse unilateral subacute neuroretinitis were followed-up using Stratus® OCT. RESULTS: Optical coherence tomography findings included retinal nerve fiber layer atrophy and focal edema where the worm was initially lodged. In two patients we could identify the worm by optical coherence tomography as an area of hiper-reflectivity. The worms were laser photocoagulated and post-treatment optical coherence tomography scanning revealed improvement of edema, nerve fiber layer thinning and a retinal hyper-reflectivity where laser had been applied. CONCLUSION: The main finding reported here is the potential of optical coherence tomography in detecting the presence of retinal nerve fiber layer atrophy and focal retinal edema in areas affected by the worm. Optical coherence tomography can be used to distinguish diffuse unilateral subacute neuroretinitis from other mimicking diseases like punctate outer retinitis, when there are no retinal fiber layer atrophy.
- ItemAcesso aberto (Open Access)Síndrome de Wolfram: relato de caso(Conselho Brasileiro de Oftalmologia, 2004-12-01) Fontes, Bruno Machado [UNIFESP]; Chen, Jane [UNIFESP]; Príncipe, André Hasler [UNIFESP]; Sallum, Juliana Maria Ferraz [UNIFESP]; Chicani, Carlos Filipe [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)Wolfram syndrome consists of the association of diabetes mellitus with optic atrophy. Other common findings are deafness, urinary tract and neurological disorders. It is an autossomic recessive disease, with incomplete penetrance and variable expressivity. The aim of this case report is to describe a patient who presents all the characteristics of Wolfram syndrome (DIDMOAD syndrome). JFP, African - American, 23 years old, presents with diabetes mellitus and insipidus, optic atrophy, deafness, peripheral polyneuropathy, autonomic neuropathy, neurogenic bladder, urinary tract dilation with recurrent infections, and azoospermia. Clinical examination, retinography, fluorescein angiogram, eletroretinography (ERG) and visual evocated potencial (VEP) revealed no retinal disorders and bilateral optic atrophy. Wolfram syndrome must be remembered in cases of optic atrophy in association with diabetes, urinary disorders, or any of the described alterations.