Navegando por Palavras-chave "Anti-Thymocyte"

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    Efeito Da Globulina Anti-Timócito E Do Everolimo Na Cinética Da Carga Viral Do Citomegalovírus Em Pacientes Transplantados Renais Soropositivos E Sem Quimioprofilaxia
    (Universidade Federal de São Paulo (UNIFESP), 2018-06-28) Basso, Geovana [UNIFESP]; Silva Junior, Helio Tedesco [UNIFESP]; http://lattes.cnpq.br/1621797721074970; http://lattes.cnpq.br/1695195960247950; Universidade Federal de São Paulo (UNIFESP)
    Introduction: Cytomegalovirus Is The Most Common Infection After Organ Solid Transplants And It Is Related With Major Morbidity, Mortality And Costs. The Use Of Mtor Inhibitors Is Associated With Lower Incidence Of Cmv Infections But Its Effect On Viral Load Has Not Been Investigated. Objective And Methods: The Aim Of This Analysis Was To Investigate And Compare The Kinetics Of Cmv Replication Using A Quantitative Nucleic Acid Amplification Testing (Qnat) During The First 6 Months After Kidney Transplantation In The Absence Of Pharmacological Prophylaxis. Results: Weekly And Simultaneously, It Was Collected Plasma Samples To Measure Pp65 Antigenemia And Cmv Qnat In 273 Cmv Positive Kidney Transplant Recipients Receiving Ragt/Tac/Evr (N=81), Bas/Tac/Evr (N=97) Or Bas/Tac/Mps (N=95) And No Pharmacological Prophylaxis. Preemptive Therapy Was Used To Prevent Cmv Disease With Pp65 Antigenemia. Qnat Was Collected Exclusively For This Analyses. The Incidence Of First Cmv Infection/Disease (2.5 Vs. 7.2 Vs. 33.7%, P=0