Navegando por Palavras-chave "Achilles tendon"

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    Achilles tendinopathy in diabetes mellitus
    (Amer Orthopaedic Foot & Ankle Soc, Inc, 2008-05-01) Batista, Fabio [UNIFESP]; Nery, Caio [UNIFESP]; Pinzur, Michael; Monteiro, Augusto Cesar; Souza, Edmisio Francisco de; Felippe, Fernando H. Z.; Alcantara, Mauricio C.; Campos, Ramon S.; Loyola Univ; Universidade Federal de São Paulo (UNIFESP); Carmino Caricchio Hosp
    Background: Plantar forefoot ulcers in individuals with diabetes often lead to deep infection and lower extremity amputation. increasing evidence suggests that the process is initiated by increased passive stiffness within the gastrocnemius-soleus musculotendinous unit. the goal of this investigation was to perform ultrasound examination of the Achilles tendon in a consecutive group of asymptomatic diabetic individuals to identify any inherent structural pathology that might be associated with the increased stiffness that appears to be associated with the development of diabetic forefoot ulcers. Materials and Methods: Seventy consecutive diabetic individuals with no past history of diabetic foot morbidity underwent ultrasonography of their Achilles tendons. Each patient was also tested for fasting glucose and glycosylated hemoglobin as a measure of diabetes control. Ten similarly aged non-diabetics with no history of Achilles tendinopathy served as controls. Results: the ultrasonography revealed disorganized tendon fibers in 62 of 70 (89%) patients, and calcification within the Achilles tendon in 53 (76%) patients. the Achilles tendon thickness averaged 5.0 (range, 4 to 8) mm. There was no correlation between patient age and Achilles tendon thickness (r = 0.292, p = 0.014); however, there was a trend for duration of disease and Achilles tendon disorganization (p = 0.073). the oldest patients also appeared to demonstrate a trend for more ultrasound-measured Achilles tendinopathy. There was no correlation between fasting glucose or glycosylated hemoglobin and Achilles tendon alterations. Conclusion: This investigation confirms structural abnormalities within the Achilles tendon of diabetic individuals that might represent biologic changes affecting the inherent stiffness that leads to increased forefoot pressure and the development of plantar forefoot ulcers. This process appears to worsen with advanced age and does not appear to be related to diabetes control.
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    Collagen Changes and Realignment Induced by Low-Level Laser Therapy and Low-Intensity Ultrasound in the Calcaneal Tendon
    (Wiley-Blackwell, 2010-08-01) Wood, Viviane Timm [UNIFESP]; Pinfildi, Carlos Eduardo [UNIFESP]; Neves, Marco Aurelio Invaldi [UNIFESP]; Parizoto, Nivaldo Antonio; Hochman, Bernardo Sergio [UNIFESP]; Ferreira, Lydia Masako [UNIFESP]; Universidade Federal de São Paulo (UNIFESP); Universidade Federal de São Carlos (UFSCar)
    Background and Objective: the treatment of calcaneal tendon injuries requires long-term rehabilitation Ultrasound (US) and low-level laser therapy (LLLT) are the most used and studied physical agents in the treatment of tendon injuries, however, only a few studies examined the effects of the combination of US and LLLT. Therefore, the purpose of this study was to investigate which treatment (the exclusive or combined use of US and LLLT) most effectively contribute to tendon healing.Study Design/Materials and Methods: This was a controlled laboratory study with 50 rats whose Achilles tendon was injured by direct trauma. the rats were randomly divided into five groups and treated for 5 consecutive days, as follows: group 1 (control) received no treatment; group 2 was treated with US alone, group 3 was treated with LLLT alone, group 4 was treated first with US followed by LLLT, and group 5 was treated first with LLLT followed by US On the sixth post-injury day, the tendons were removed and examined by polarized light microscopy. the organization of collagen fibers was assessed by birefringence measurements Picrosirius-stained sections were examined for the presence of types I and Ill collagen.Results: There was a significantly higher organization of collagen fibers in group 2 (US) than in the control group (P=0.03). the amount of type I collagen found in groups 2 (US), 3 (LLLT), and 5 (LLLT+US) was significantly higher than that in the control group (P <= 0.01), but no significant differences were found between treatment groups. There were no differences in the amount of type III collagen between groups.Conclusion: Ultrasound, LLLT, and the combined use of LLLT and US resulted in greater synthesis of type I collagen; US was also effective in increasing collagen organization in the early stages of the healing process Lasers Surg. Med. 42 559-565, 2010 (C) 2010 Wiley-Liss, Inc.
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    Diferentes potências da terapia a laser de baixa intensidade no reparo tendíneo, em ratos
    (Universidade Federal de São Paulo (UNIFESP), 2009-09-30) Neves, Marco Aurelio Invaldi [UNIFESP]; Hochman, Bernardo [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)
    Introduction: Calcaneous tendon is one of the most damaged tendons, and its healing may last from weeks to months to be completed. In the search after speeding tendon repair, low intensity laser therapy has shown favorable effect. Objective: To assess the effect of 40, 60, 80 and 100mW powers of low level laser on the process of tissue repair in partial lesion calcaneous tendon in rats. Methods: The was used 830-nm GaAlAs diode laser operating at output powers of 40, 60, 80 and 100 mW and energy density of 30 J/cm2 on the repair of partial calcaneal tendon ruptures in rats. A partial tendon rupture was induced in all animals, which were treated with laser irradiation for 5 consecutive days. Six days after injury, the injured tendons were removed and examined by polarized light microscopy. Results: Collagen fiber organization was evaluated by birefringence measurements, and collagen content was determined by picrosirius red staining. It was observed that the higher the output power (60-100 mW) the greater was the amount of type III collagen (P < 0.01). The amount of type I collagen was significantly greater (P = 0.05) in the 80-mW group than in the control group (sham stimulation). A non-statistically significant improvement in the realignment of collagen fibers was observed in the irradiated groups. Conclusion: Low-level laser therapy resulted in significantly greater amounts of type III collagen (output powers of 60 mW or more) and type I collagen (output power of 80 mW), however, no significant differences between groups were found in the realignment of collagen fibers.
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    Low-level laser therapy in IL-1 beta, COX-2, and PGE2 modulation in partially injured Achilles tendon
    (Springer, 2015-01-01) Jesus, Julio Fernandes de [UNIFESP]; Spadacci-Morena, Diva Denelle; Anjos Rabelo, Nayra Deise dos; Pinfildi, Carlos Eduardo [UNIFESP]; Fukuda, Thiago Yukio; Plapler, Helio [UNIFESP]; Universidade Federal de São Paulo (UNIFESP); Inst Butantan; Univ Nove Julho UNINOVE; ISCMSP
    This study evaluated IL-1 beta, COX-2, and PGE2 modulation in partially injured Achilles tendons treated with low-level laser therapy (LLLT). Sixty-five male Wistar rats were used. Sixty were submitted to a direct injury on Achilles tendon and then distributed into six groups: LASER 1 (a single LLLT application), LASER 3 (three LLLT applications), and LASER 7 (seven LLLT applications) and Sham 1, 3, and 7 (the same injury but LLLT applications were simulated). the five remaining animals were allocated at control group (no procedure performed). LLLT (780 nm) was applied with 70 mW of mean power and 17.5 J/cm(2) of fluency for 10 s, once a day. the tendons were surgically removed and assessed immunohistochemically for IL-1 beta, COX-2, and PGE2. in comparisons with control (IL-1 beta: 100.5 +/- 92.5 / COX-2: 180.1 +/- 97.1 / PGE2: 187.8 +/- 128.8) IL-1 beta exhibited (mean +/- SD) near-normal level (p > 0.05) at LASER 3 (142.0 +/- 162.4). COX-2 and PGE2 exhibited near-normal levels (p > 0.05) at LASER 3 (COX-2: 176.9 +/- 75.4 / PGE2: 297.2 +/- 259.6) and LASER 7 (COX-2: 259.2 +/- 190.4 / PGE2: 587.1 +/- 409.7). LLLT decreased Achilles tendon's inflammatory process.