Browsing by Subject "zidovudine"

Now showing items 1-3 of 3

    • Comparative studies of two-times-daily versus three-times-daily indinavir in combination with zidovudine and lamivudine 

      Haas, D. W.; Arathoon, E.; Thompson, M. A.; Pedro, R. D.; Gallant, J. E.; Uip, D. E.; Currier, J.; Noriega, L. M.; Lewi, David S. [UNIFESP]; Uribe, P.; Benetucci, J.; Cahn, P.; Paar, D.; White, C. A.; Collier, A. C.; Ramirez-Ronda, C. H.; Harvey, C.; Chung, M.; Mehrotra, D.; Chodakewitz, J.; Nguyen, B. Y.; Protocol 054 069 Study Teams (Lippincott Williams & Wilkins, 2000-09-08)
      Objectives: To compare the efficacy and safety of two-times-daily versus three-times-daily indinavir in combination with zidovudine and lamivudine. Design: Two multicenter, open-label, randomized 24-week studies.Methods: ...

    • Effects of short-term zidovudine exposure on mitochondrial DNA content and succinate dehydrogenase activity of rat skeletal muscle cells 

      Kiyomoto, Beatriz H. [UNIFESP]; Tengan, Celia H. [UNIFESP]; Godinho, Rosely O. [UNIFESP] (Elsevier B.V., 2008-05-15)
      Long-term use of zidovudine (AZT) may cause mitochondrial abnormalities in various tissues, including a toxic myopathy in AIDS patients associated with mitochondrial DNA (mtDNA) depletion. in the present study, we examine ...

    • Multivariate spectroscopic determination of the lamivudine-zidovudine association 

      Cordeiro, Gilcélia Aparecida; Nagata, Noemi; Messerschmidt, Iara; Peralta-Zamora, Patricio; Rodrigues, Leticia Norma Carpentieri [UNIFESP] (Sociedade Brasileira de Química, 2011-02-01)
      The multivariate spectroscopic determination of lamivudine-zidovudine associations was carried out by partial least square regression (PLS). This model was developed from 20 synthetic mixtures using mean-centered spectral ...