Now showing items 1-10 of 22

    • The Anti-Inflammatory Potential of Mimosa caesalpiniifolia Following Experimental Colitis: Role of COX-2 and TNF-Alpha Expression 

      Silva, Marcelo Jose Dias; Vilegas, Wagner; Silva, Marcelo Aparecido da; Paiotti, Ana Paula Ribeiro [UNIFESP]; Pastrelo, Mauricio Mercaldi [UNIFESP]; Ruiz, Pedro Luiz Menin [UNIFESP]; Moura, Carolina Foot Gomes de [UNIFESP]; Oshima, Celina Tizuko Fujiyama [UNIFESP]; Ribeiro, Daniel Araki [UNIFESP] (Georg Thieme Verlag Kg, 2018)
      The aim of this study was to evaluate the preventive and/or protective action of Mimosa caesalpiniifolia (M. caesalpiniifolia) following experimental colitis in rats. The rats were randomized into ten groups (n = 10 per ...

    • The anti-inflammatory potential of phenolic compounds in grape juice concentrate (G8000 (TM)) on 2,4,6-trinitrobenzene sulphonic acid-induced colitis 

      Ribeiro Paiotti, Ana Paula [UNIFESP]; Neto, Ricardo Artigiani [UNIFESP]; Marchi, Patricia [UNIFESP]; Silva, Roseane Mendes [UNIFESP]; Pazine, Vanessa Lima [UNIFESP]; Noguti, Juliana [UNIFESP]; Pastrelo, Mauricio Mercaldi [UNIFESP]; Boiago Golluecke, Andrea Pittelli; Miszputen, Sender Jankiel [UNIFESP]; Ribeiro, Daniel Araki [UNIFESP] (Cambridge Univ Press, 2013-09-28)
      Chronic inflammatory bowel disease is characterised by an up-regulation of the synthesis and release of a variety of pro-inflammatory mediators leading to excessive tissue injury. Flavonoids are able to inhibit enzymes ...

    • The association between TNF-alpha and erectile dysfunction complaints 

      Matos, G. [UNIFESP]; Hirotsu, C. [UNIFESP]; Alvarenga, T. A. [UNIFESP]; Cintra, F. [UNIFESP]; Bittencourt, L. [UNIFESP]; Tufik, S. [UNIFESP]; Andersen, M. L. [UNIFESP] (Wiley-Blackwell, 2013-11-01)
      Inflammatory markers like tumour necrosis factor-alpha (TNF-) have been related to erectile dysfunction (ED) and may interact with other cardiovascular risk factors such as obstructive sleep apnoea syndrome (OSAS). the aim ...

    • Circulating levels of sTNFR1 as a marker of severe clinical course in schizophrenia 

      Noto, Cristiano [UNIFESP]; Gadelha, Ary [UNIFESP]; Belangero, Sintia I. [UNIFESP]; Spindola, Leticia M. [UNIFESP]; Rocha, Natalia Pessoa; Miranda, Aline Silva de; Teixeira, Antonio Lucio; Cardoso Smith, Marilia Arruda [UNIFESP]; Mari, Jair de Jesus [UNIFESP]; Bressan, Rodrigo Affonseca [UNIFESP]; Brietzke, Elisa [UNIFESP] (Elsevier B.V., 2013-04-01)
      Background: Schizophrenia (SZ) has been associated with an imbalance in the inflammatory cytokine TNF-alpha. the objectives of this study were to compare TNF-alpha and its soluble receptors' serum levels in individuals ...

    • Differential inhibitory mechanism of cyclic AMP on TNF-alpha and IL-12 synthesis by macrophages exposed to microbial stimuli 

      Procópio, Daniela O. [UNIFESP]; Teixeira, Mauro M.; Camargo, Maristela M.; Travassos, Luiz R.; Ferguson, Michael AJ; Almeida, Igor C.; Gazzinelli, Ricardo T. (Stockton Press, 1999-07-01)
      1 Microbial stimuli such as bacterial lipopolysaccharide (LPS) or glycosylphosphatidylinositol-mucins derived from Trypanosoma cruzi trypomastigotes (tGPI-mucins) are effective stimulators of the synthesis of cytokines by ...

    • Effect of COX-2 inhibitor lumiracoxib and the TNF-alpha antagonist etanercept on TNBS-induced colitis in Wistar rats 

      Ribeiro Paiotti, Ana Paula [UNIFESP]; Ribeiro, Daniel Araki [UNIFESP]; Silva, Roseane Mendes [UNIFESP]; Marchi, Patricia [UNIFESP]; Oshima, Celina Tizuko Fujiyama [UNIFESP]; Artigiani Neto, Ricardo [UNIFESP]; Miszputen, Sender Jankiel [UNIFESP]; Franco, Marcello [UNIFESP] (Springer, 2012-06-01)
      Crohn's disease (CD) is associated with gut barrier dysfunction. Besides the baseline barrier defect, a subgroup of patients also expresses an intestinal barrier hyperresponsiveness to nonsteroidal anti-inflammatory drugs. ...

    • Effect of natural porcine surfactant in Staphylococcus aureus induced pro-inflammatory cytokines and reactive oxygen species generation in monocytes and neutrophils from human blood 

      Guevara, Yuliannis Lugones Ladron de; Hidalgo, Odalys Blanco; Santos, Sidneia Sousa [UNIFESP]; Brunialti, Milena Karina Coló [UNIFESP]; Faure, Roberto; Salomão, Reinaldo [UNIFESP] (Elsevier B.V., 2014-08-01)
      Surfacen (R) is a clinical surfactant preparation of porcine origin. in the present study, we have evaluated the effect of Surfacen (R) in the modulation of oxidative burst in monocytes and neutrophils in human blood and ...

    • Effects of Pentoxifylline on Inflammation and Lung Dysfunction in Ventilated Septic Animals 

      Oliveira-Junior, Itamar Souza [UNIFESP]; Souza Oliveira, Wagner Rogerio [UNIFESP]; Cavassani, Samia Santos [UNIFESP]; Colo Brunialti, Milena Karina; Salomao, Reinaldo [UNIFESP] (Lippincott Williams & Wilkins, 2010-04-01)
      Acute respiratory distress syndrome secondary to sepsis is associated with high morbidity and mortality. the purpose of this study was to characterize the effects of ventilatory strategy and the modulating activity of ...

    • Endurance training induces depot-specific changes in IL-10/TNF-alpha ratio in rat adipose tissue 

      Lira, F. S.; Rosa, J. C. [UNIFESP]; Yamashita, A. S.; Koyama, C. H.; Batista, M. L.; Seelaender, M. (Elsevier B.V., 2009-02-01)
      White adipose tissue (WAT) is the source of pro- and anti-inflammatory cytokines and recently, it has been recognized as an important source of interleukin 10 (IL-10). Acute physical exercise is known to induce an ...

    • Etanercept attenuates TNBS-induced experimental colitis: role of TNF-alpha expression 

      Ribeiro Paiotti, Ana Paula [UNIFESP]; Miszputen, Sender Jankiel [UNIFESP]; Oshima, Celina Tizuko Fujiyama [UNIFESP]; Artigiani Neto, Ricardo [UNIFESP]; Ribeiro, Daniel Araki [UNIFESP]; Franco, Marcello [UNIFESP] (Springer, 2011-10-01)
      Crohn's disease (CD) is associated with gut barrier dysfunction. Tumour necrosis factor-alpha (TNF-alpha) plays an important role into the pathogenesis of several inflammatory diseases because its expression is increased ...