Browsing by Subject "Proteomics"
Now showing items 1-10 of 17
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Avaliação de proteínas seminais relacionadas ao estresse oxidativo e sua associação com o nível de peroxidação lipídica em homens normozoospérmicos com ou sem fatores clínicos de agravo à fertilidade.
(Universidade Federal de São Paulo (UNIFESP), 2018-01-23)Objective: To verify the seminal levels of SOD1, PRDX1, S100A9, APOA4 and GSTP1 proteins as biomarkers of semen lipid peroxidation. Methods: A cross-sectional study was carried out with 100 normozoospermic men, of whom 25 ...
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Avaliação do efeito precoce da orquiectomia radical unilateral no perfil de proteínas do plasma seminal de homens portadores de tumor de células germinativas de testículo
(Universidade Federal de São Paulo (UNIFESP), 2019-11-06)Objective: To evaluate the effect of orchiectomy on the seminal plasma proteomic profile of men with testicular germ cell tumors. Methods: Seventeen men with Testicular Germ Cell Tumors provided one semen sample before ...
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Avaliação do perfil proteômico na saliva em trabalhadores da cadeia produtiva de joias, semijoias e bijuterias de Limeira, SP
(Universidade Federal de São Paulo (UNIFESP), 2019-06-27)City of Limeira, located in Brazil, consolidates a region of jewelry and fashion adornment production with homemade and informal processes of assembly, welding and electroplating of jewels, providing a scenario of outsourced ...
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Estudo bioanalítico e proteômico de sarcoma de Hippopotumus amphibius
(Universidade Federal de São Paulo, 2014-10-24)This project aims to analyse the protein profile of a Hippopotamus amphibius' sarcoma. Using proteomic analysis on three tissue samples of an animal that passed away due to the advanced stage of the disease, an origin ...
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Estudo das vias proteômicas do plasma seminal e dos espermatozoides associadas à infertilidade masculina
(Universidade Federal de São Paulo (UNIFESP), 2018-05-08)Objective: The seminal plasma and sperm protein profile is essential for adequate sperm function, and, consequently, for male fertility. Thus, proteomic studies have been undertaken in order to understand underlying ...
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Estudo do perfil proteômico do tamanduá-mirim (T. tetradactyla)
(Universidade Federal de São Paulo, 2014-12-17)The increase in anthropological impacts led to the decrease of places that were the natural habitat of several species of animals. This occurrence brought a disadvantage to animal life and the conservation of these species. ...
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Experimental varicocoele in rats affects mechanisms that control expression and function of the androgen receptor
(Wiley-Blackwell, 2013-09-01)Varicocoele is an important cause of male infertility. Normal male reproductive function and fertility depends on a delicate balance between androgen receptor (AR) and the classic oestrogen receptors ESR1 (ER alpha) and ...
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Hippocampal proteomic profile in temporal lobe epilepsy
(Liga Brasileira de Epilepsia (LBE), 2012-01-01)In this study we used proteomics approaches to obtain the protein profile of human epileptic hippocampi (N=6) and control hippocampi obtained from autopsy (N=6). We used two-dimensional gel electrophoresis (2-D) coupled ...
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Improving the bothropic antivenom through affinity chromatography and proteomics
(Universidade Federal de São Paulo, 2023-02-06)Every year, more than 100,000 deaths occur worldwide as a consequence of snakebite envenoming, and around 400,000 people suffer lasting injuries or disfigurements. The World Health Organization added snakebite envenoming ...
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Increased chemical acetylation of peptides and proteins in rats after daily ingestion of diacetyl analyzed by Nano-LC-MS/MS
(Peerj Inc, 2018)Background. Acetylation alters several protein properties including molecular weight, stability, enzymatic activity, protein protein interactions, and other biological functions. Our previous findings demonstrating that ...
