Browsing by Subject "Peptides"

Now showing items 1-10 of 19

    • Absence of oxytocin in the central nervous system of the snake Bothrops jararaca 

      Lazari, Maria de Fatima Magalhaes [UNIFESP]; Alponti, Rafaela Fadoni; Freitas, Thalma Ariani; Breno, Maria Cristina; Conceição, Isaltino Marcelo da; Silveira, Paulo Flavio (Springer, 2006-11-01)
      We used four complementary techniques to investigate the presence of oxytocin peptide in the hypophysis and brain of the snake Bothrops jararaca. A high-pressure liquid chromatographic analysis failed to show oxytocin in ...

    • Analogues containing the paramagnetic amino acid TOAC as substrates for angiotensin 1-converting enzyme 

      Teixeira, Luis Gustavo de Deus [UNIFESP]; Bersanetti, Patricia Alessandra [UNIFESP]; Schreier, Shirley; Carmona, Adriana Karaoglanovic [UNIFESP]; Nakaie, Clovis Ryuichi [UNIFESP] (Elsevier B.V., 2007-05-29)
      The angiotensin I-converting enzyme (ACE) converts the decapeptide angiotensin I (Ang I) into angiotensin II by releasing the C-terminal dipeptide. A novel approach combining enzymatic and electron paramagnetic resonance ...

    • Caracterização de marcadores de virulência em Paracoccidioides brasiliensis 

      Kioshima, Érika Seki [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 2009-06-24)
      Paracoccidioidomycosis (PCM) is a human systemic granulomatous disease, prevalent in South America, caused by a thermodimorphic fungus, Paracoccidioides brasiliensis. This fungus presents complex antigenic structure and ...

    • A diversidade estrutural de peptídeos potenciadores da bradicinina da Bothrops jararaca (Bj-BPPs) proporciona ações sinérgicas no sistema cardiovascular 

      Morais, Kátia Luciano Pereira [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 2010-03-31)
      Our laboratory has shown that one gene codes for the protein precursor that yields the natriuretic peptide type C (CNP) after having been processed, along with a variety of proline-rich peptides, known as bradykinin-potentiating ...

    • Efeito Antitrombótico Do Inibidor Quimérico De Calicreína E De Peptídeos Estruturalmente Relacionados Em Modelo De Trombose Arterial Em Camundongos 

      Medina, Andre Fernando [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 2018-08-30)
      Thrombotic Disorders Are The Most Common Causes Of Morbidity And Mortality In The World. Several Evidences Suggest That Factor Xii, Factor Xi And Pre-Kallikrein Are Majority Targets To Extrinsic Pathway Proteases, Such As ...

    • Effects of the angiotensin II Ala-scan analogs in erythrocytic cycle of Plasmodium falciparum (in vitro) and Plasmodium gallinaceum (ex vivo) 

      Silva, Adriana Farias; Silva, Leandro de Souza; Alves, Flavio Lopes [UNIFESP]; TorossianTorres, Marcelo Der; SaPinheiro, Ana Acacia de; Miranda, Antonio; LaraCapurro, Margareth; Oliveira, Vani Xavier (Elsevier B.V., 2015-06-01)
      The anti-plasmodium activity of angiotensin II and its analogs have been described in different plasmodium species. Here we synthesized angiotensin II Ala-scan analogs to verify peptide-parasite invasion preservation with ...

    • The Importance of Ring Size and Position for the Antiplasmodial Activity of Angiotensin II Restricted Analogs 

      Torres, Marcelo Der Torossian; Silva, Adriana Farias; Alves, Flavio Lopes [UNIFESP]; Capurro, Margareth Lara [UNIFESP]; Miranda, Antonio [UNIFESP]; Oliveira Junior, Vani Xavier (Springer, 2014-09-01)
      Malaria is caused by the protozoa Plasmodium and is responsible for approximately one million deaths annually. the antimalarial effects of angiotensin II and its analogs against Plasmodium gallinaceum and falciparum have ...

    • Neurolysin Knockout Mice Generation and Initial Phenotype Characterization 

      Cavalcanti, Diogo M. L. P.; Castro, Leandro M. [UNIFESP]; Rosa Neto, José Cesar [UNIFESP]; Seelaender, Marilia; Neves, Rodrigo X.; Oliveira, Vitor [UNIFESP]; Forti, Fabio L.; Iwai, Leo K.; Gozzo, Fabio C.; Todiras, Mihail; Schadock, Ines; Barros, Carlos C.; Bader, Michael [UNIFESP]; Ferro, Emer Suavinho [UNIFESP] (Amer Soc Biochemistry Molecular Biology Inc, 2014-05-30)
      The oligopeptidase neurolysin (EC 3.4.24.16; Nln) was first identified in rat brain synaptic membranes and shown to ubiquitously participate in the catabolism of bioactive peptides such as neurotensin and bradykinin. ...

    • Oxintomodulina e obesidade 

      Pimentel, Gustavo Duarte [UNIFESP]; Mota, João Felipe [UNIFESP]; Oyama, Lila Missae [UNIFESP] (Pontifícia Universidade Católica de Campinas, 2009-10-01)
      Since the discovery of leptin, great advances occurred in the characterization of hypothalamic mechanisms involved in the control of food intake and oxyntomodulin is currently recognized as a homeostasis energy regulator. ...

    • Peptideos derivados da gp43 de Paracoccidioides brasiliensis inibem a fagocitose 

      Konno, Adriana Yumi de Camargo [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 2008)
      Paracoccidioidomicose (PCM) é uma doença granulomatosa sistêmica causada pelo fungo dimórfico térmico Paracoccidioides brasiliensis. O principal antígeno desse fungo é uma glicoproteína de 43-KDa. Gp43 possui ...