Browsing by Subject "Orexin"
Now showing items 1-6 of 6
-
Avaliação dos efeitos da privação alimentar sobre o condicionamento ambiental induzido por diferentes drogas de abuso
(Universidade Federal de São Paulo (UNIFESP), 2017-03-31)Cumulative experimental evidence points to the existence of positive correlation between the exposure to different stressors and increased vulnerability to addiction. There is a need to search for stress markers which more ...
-
Controle central da atividade física espontânea em camundongos submetidos ou não à restrição calórica durante o processo de envelhecimento
(Universidade Federal de São Paulo, 2022-12-13)A atividade física espontânea (AFE) engloba toda forma de atividade física, seja em casa, no trabalho ou no lazer. Apesar de negligenciada, ela é um componente importante do balanço energético. Dados anteriores do nosso ...
-
Investigação da ritmicidade circadiana e dos efeitos da privação de sono paradoxal na resposta dos sistemas MCHérgico e Orexinérgico
(Universidade Federal de São Paulo (UNIFESP), 2019-04-25)Introduction: Melanin concentrating hormone (MCH) and Orexin are neuropeptides synthesized in distinct groups of neurons of the lateral hypothalamic area that act in a reciprocal way in the regulation of sleep/wake states. ...
-
Paradoxical sleep deprivation activates hypothalamic nuclei that regulate food intake and stress response
(Elsevier B.V., 2009-09-01)A large body of evidence has shown that prolonged paradoxical sleep deprivation (PSD) results in hypothalamic-pituitary-adrenal (HPA) axis activation, and in loss of body weight despite an apparent increase of food intake, ...
-
Participação do sistema da orexina na sensibilização comportamental ao efeito estimulante do etanol em camundongos machos
(Universidade Federal de São Paulo (UNIFESP), 2011-03-30)Orexins are two neuropeptides, orexin-A and orexin-B, derived from the same precursor gene (pre-pro-orexin) produced by a few thousand neurons located in the perifornical area of the lateral hypothalamus. Despite having a ...
-
Subchronical treatment with Fluoxetine modifies the activity of the MCHergic and hypocretinergic systems. Evidences from peptide CSF concentration and gene expression
(Elsevier Science Bv, 2016)In the postero-lateral hypothalamus are located two neuronal systems that utilize the neuropeptides melanin-concentrating hormone (MCH) and hypocretins (also called orexins) as neuromodulators. These systems have reciprocal ...
