Now showing items 1-8 of 8

    • Change in central kinin B2 receptor density after exercise training in rats 

      Caetano, Ariadiny Lima; Viel, Tania Araujo; Queiroz Prado Bittencourt, Maria Fernanda; Araujo, Mariana Silva [UNIFESP]; De Angelis, Katia; Buck, Hudson Sousa (Elsevier B.V., 2010-12-08)
      Cardiovascular responses elicited by the stimulation of kinin B2 receptors in the IV cerebral ventricle paratrigeminal nucleus or in the thoracic spinal cord are similar to those observed during an exercise bout Considering ...

    • Effect of the bradykinin 1 receptor antagonist SSR240612 after oral administration in Mycobacterium tuberculosis-infected mice 

      Rodrigues-Junior, Valnes S.; Pail, Priscilla B.; Villela, Anne D.; Falcao, Virginia C. A.; Dadda, Adilio S.; Abbadi, Bruno L.; Pesquero, João Bosco [UNIFESP]; Santos, Diogenes S.; Basso, Luiz A.; Campos, Maria M. (Churchill Livingstone, 2018)
      The role, if any, played by the kinin system in tuberculosis infection models, either in vivo or in vitro, was investigated. The effects of Mycobacterium tuberculosis infection on C57BL/6 wild type, B1R-/-, B2R-/- and ...

    • Effects of transforming growth factor-beta in the development of inflammatory pseudotumour-like lesions in a murine model 

      Guariniello, Luciana Doria [UNIFESP]; Correa, Mariangela [UNIFESP]; Jasiulionis, Miriam Galvonas [UNIFESP]; Machado Junior, Joel [UNIFESP]; Silva Junior, Jose Antonio [UNIFESP]; Pesquero, João Bosco [UNIFESP]; Carneiro, Celia Regina Whitaker [UNIFESP] (Blackwell Publishing, 2006-06-01)
      Alterations in transforming growth factor (TGF)-beta signalling have been frequently implicated in human cancer, and an important mechanism underlying its pro-oncogenic pature is suppression of the host antitumour immune ...

    • Evidence that kinin B-2 receptor expression is upregulated by endothelial overexpression of B-1 receptors 

      Rodrigues, Eliete da Silva [UNIFESP]; Silva, Rafael Filippelli da [UNIFESP]; Martin, Renan Paulo [UNIFESP]; Oliveira, Suzana Macedo de [UNIFESP]; Nakaie, Clovis Ryuichi [UNIFESP]; Sabatini, Regiane Angélica [UNIFESP]; Merino, Vanessa Ferreira; Pesquero, João Bosco [UNIFESP]; Bader, Michael [UNIFESP]; Shimuta, Suma Imura [UNIFESP] (Elsevier B.V., 2013-04-01)
      Bradykinin (BK) and des-Arg(9)-bradykinin (DBK) of kallikrein-kinin system exert its effects mediated by the B-2 (B2R) and B-1 (B1R) receptors, respectively. It was already shown that the deletion of kinin B1R or of B2R ...

    • Kallikrein 1 is overexpressed by astrocytes in the hippocampus of patients with refractory temporal lobe epilepsy, associated with hippocampal sclerosis 

      Rodrigues Simoes, Priscila Santos [UNIFESP]; Perosa, Sandra Regina [UNIFESP]; Arganaraz, Gustavo Adolfo; Yacubian, Elza Márcia Targas [UNIFESP]; Carrete, Henrique [UNIFESP]; Centeno, Ricardo Silva [UNIFESP]; Vasconcellos Varella, Pedro Paulo [UNIFESP]; Carvalho Santiago, Joselita Ferreira [UNIFESP]; Canzian, Mauro; Silva, Jose Antonio; Mortara, Renato Arruda [UNIFESP]; Amado, Debora [UNIFESP]; Cavalheiro, Esper Abrao [UNIFESP]; Naffah Mazzacoratti, Maria da Graca [UNIFESP] (Elsevier B.V., 2011-03-01)
      Kallikrein 1 (hK1) is a tissue enzyme responsible for kinin release in inflammatory cascade. This study was delineated to study the distribution and the co-localization of hK1 and kinin B1 and B2 receptors with glial and/or ...

    • Kinin receptors of the central-nervous-system of spontaneously hypertensive rats related to the pressor-response to bradykinin 

      Martins, Domingos Tabajara de Oliveira [UNIFESP]; Fior-Chadi, Debora Rejane [UNIFESP]; Nakaie, Clovis Ryuichi [UNIFESP]; Lindsey, Charles Julian [UNIFESP] (Stockton Press, 1991-08-01)
      1 Kinin analogues bradykinin (BK), T-kinin, Met-Lys-BK, Lys-Lys-BK, Des-Arg9-BK with agonist activity and D-Arg0-Hyp3-Thi5,8-D-Phe7-BK (DAHTDBK) and Arg9-Leu8-BK with antagonist activity were injected into the posterior ...

    • The non-peptide kinin receptor antagonists FR 173657 and SSR 240612: Preclinical evidence for the treatment of skin inflammation 

      Pietrovski, Evelise Fernandes; Otuki, Michel Fleith; Regoli, Domenico; Bader, Michael; Pesquero, Joao Bosco [UNIFESP]; Cabrini, Daniela Almeida; Zampronio, Aleksander Roberto (Elsevier B.V., 2009-01-08)
      Peptide and non-peptide kinin receptor antagonists were evaluated in cutaneous inflammation models in mice. Topical and i.p. application of kinin B(1) and B(2) receptor antagonists caused a significant inhibition of the ...

    • Role of kinin B1 and B2 receptors in memory consolidation during the aging process of mice 

      Resk Lemos, Mayra Tolentino; Amaral, Fabio Agostini; Dong, Karis Ester; Queiroz Prado Bittencourt, Maria Fernanda; Caetano, Ariadiny Lima; Pesquero, Joao Bosco [UNIFESP]; Viel, Tania Araujo; Buck, Hudson Sousa (Churchill Livingstone, 2010-04-01)
      Under physiological conditions, elderly people present memory deficit associated with neuronal loss. This pattern is also associated with Alzheimer's disease but, in this case, in a dramatically intensified level. Kinin ...