TFOS DEWS II Management and Therapy Report

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dc.citation.issue3]
dc.citation.volume15]
dc.contributor.authorJones, Lyndon
dc.contributor.authorDownie, Laura E.
dc.contributor.authorKorb, Donald
dc.contributor.authorBenitez-del-Castillo, Jose M.
dc.contributor.authorDana, Reza
dc.contributor.authorDeng, Sophie X.
dc.contributor.authorDong, Pham N.
dc.contributor.authorGeerling, Gerd
dc.contributor.authorHida, Richard Yudi
dc.contributor.authorLiu, Yang
dc.contributor.authorSeo, Kyoung Yul
dc.contributor.authorTauber, Joseph
dc.contributor.authorWakamatsu, Tais H. [UNIFESP]
dc.contributor.authorXu, Jianjiang
dc.contributor.authorWolffsohn, James S.
dc.contributor.authorCraig, Jennifer P.
dc.coverageAmsterdam
dc.date.accessioned2020-06-26T16:30:28Z
dc.date.available2020-06-26T16:30:28Z
dc.date.issued2017
dc.description.abstractThe members of the Management and Therapy Subcommittee undertook an evidence-based review of current dry eye therapies and management options. Management options reviewed in detail included treatments for tear insufficiency and lid abnormalities, as well as anti-inflammatory medications, surgical approaches, dietary modifications, environmental considerations and complementary therapies. Following this extensive review it became clear that many of the treatments available for the management of dry eye disease lack the necessary Level 1 evidence to support their recommendation, often due to a lack of appropriate masking, randomization or controls and in some cases due to issues with selection bias or inadequate sample size. Reflecting on all available evidence, a staged management algorithm was derived that presents a step-wise approach to implementing the various management and therapeutic options according to disease severity. While this exercise indicated that differentiating between aqueous-deficient and evaporative dry eye disease was critical in selecting the most appropriate management strategy, it also highlighted challenges, based on the limited evidence currently available, in predicting relative benefits of specific management options, in managing the two dry eye disease subtypes. Further evidence is required to support the introduction, and continued use, of many of the treatment options currently available to manage dry eye disease, as well as to inform appropriate treatment starting points and understand treatment specificity in relation to dry eye disease subtype. (C) 2017 Elsevier Inc. All rights reserved.en
dc.description.affiliationUniv Waterloo, Sch Optometry & Vis Sci, Ctr Contact Lens Res, Waterloo, ON, Canada
dc.description.affiliationUniv Melbourne, Dept Optometry & Vis Sci, Parkville, Vic, Australia
dc.description.affiliationKorb & Associates, Boston, MA USA
dc.description.affiliationUniv Complutense, Dept Ophthalmol, Madrid, Spain
dc.description.affiliationHarvard Med Sch, Massachusetts Eye & Ear Infirm, Dept Ophthalmol, Boston, MA USA
dc.description.affiliationUCLA, Stein Eye Inst, Los Angeles, CA USA
dc.description.affiliationVietnam Natl Inst Ophthalmol, Dept Corneal & External Dis, Hanoi, Vietnam
dc.description.affiliationUniv Hosp Duesseldorf, Dept Ophthalmol, Dusseldorf, Germany
dc.description.affiliationUniv Sao Paulo, Dept Ophthalmol, Santa Casa Sao Paulo, Sao Paulo, Brazil
dc.description.affiliationMassachusetts Eye & Ear, Schepens Eye Res Inst, Boston, MA USA
dc.description.affiliationYonsei Univ, Med Coll, Dept Ophthalmol, Seoul, South Korea
dc.description.affiliationTauber Eye Ctr, Kansas City, MO USA
dc.description.affiliationUniv Fed Sao Paulo, Sao Paulo Hosp, Paulista Sch Med, Dept Ophthalmol & Visual Sci, Sao Paulo, Brazil
dc.description.affiliationFudan Univ, Eye & ENT Hosp, Dept Ophthalmol & Visual Sci, Shanghai, Peoples R China
dc.description.affiliationAston Univ, Ophthalm Res Grp, Birmingham, W Midlands, England
dc.description.affiliationUniv Auckland, New Zealand Natl Eye Ctr, Dept Ophthalmol, Auckland, New Zealand
dc.description.affiliationUnifespUniv Fed Sao Paulo, Sao Paulo Hosp, Paulista Sch Med, Dept Ophthalmol & Visual Sci, Sao Paulo, Brazil
dc.description.sourceWeb of Science
dc.format.extent575-628
dc.identifierhttp://dx.doi.org/10.1016/j.jtos.2017.05.006]
dc.identifier.citationOcular Surface. Amsterdam, v. 15, n. 3, p. 575-628, 2017.
dc.identifier.doi10.1016/j.jtos.2017.05.006
dc.identifier.issn1542-0124
dc.identifier.urihttps://repositorio.unifesp.br/handle/11600/53557
dc.identifier.wosWOS:000407081200010
dc.language.isoeng
dc.publisherElsevier Science Bv
dc.relation.ispartofOcular Surface
dc.rightsACESSO RESTRITO
dc.subjectDry eye diseaseen
dc.subjectDry eye workshopen
dc.subjectManagementen
dc.subjectTFOS DEWS IIen
dc.subjectTherapyen
dc.titleTFOS DEWS II Management and Therapy Reporten
dc.typeArtigo
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