Measurement of the nonlinear optical response of low-density lipoprotein solutions from patients with periodontitis before and after periodontal treatment: evaluation of cardiovascular risk markers

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dc.contributor.authorMonteiro, Andrea M.
dc.contributor.authorJardini, Maria A. N.
dc.contributor.authorGiampaoli, Viviana
dc.contributor.authorAlves, Sarah [UNIFESP]
dc.contributor.authorFigueiredo Neto, Antonio M.
dc.contributor.authorGidlund, Magnus
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.contributor.institutionSão Paulo State Univ
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.date.accessioned2016-01-24T14:27:59Z
dc.date.available2016-01-24T14:27:59Z
dc.date.issued2012-11-01
dc.description.abstractThe Z-Scan (ZS) technique in the thermal regime has been used to measure the nonlinear optical response of low-density lipoprotein (LDL). the ZS technique is carried out in LDL from 40 patients with chronic periodontitis before and after three, six, and 12 months of periodontal treatment. Clinical parameters such as probing depths, bleeding on probing, total and differential white blood cells counts, lipid profiles, cytokine levels, and antibodies against oxidized LDL are also determined and compared over time. Before the treatment, the ZS experimental results reveal that the LDL particles of these patients are heavily modified. Only after 12 months of the periodontal treatment, the ZS results obtained reveal behavioral characteristics of healthy particles. This conclusion is also supported by complementary laboratorial analysis showing that the periodontal treatment induces systemic changes in several inflammatory markers. (C) 2012 Society of Photo-Optical Instrumentation Engineers (SPIE). [DOI: 10.1117/1.JBO.17.11.115004]en
dc.description.affiliationUniv São Paulo, Inst Biomed Sci, BR-05508900 São Paulo, Brazil
dc.description.affiliationSão Paulo State Univ, Sch Dent Sao Jose dos Campos, BR-12245000 Sao Jose Dos Campos, SP, Brazil
dc.description.affiliationUniv São Paulo, Inst Math & Stat, BR-05508090 São Paulo, Brazil
dc.description.affiliationUniversidade Federal de São Paulo, BR-09972270 Diadema, SP, Brazil
dc.description.affiliationUniv São Paulo, Inst Phys, BR-05315970 São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, BR-09972270 Diadema, SP, Brazil
dc.description.sourceWeb of Science
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.description.sponsorshipINCT-FCX
dc.description.sponsorshipINCT-INAMI
dc.format.extent7
dc.identifierhttp://dx.doi.org/10.1117/1.JBO.17.11.115004
dc.identifier.citationJournal of Biomedical Optics. Bellingham: Spie-soc Photo-optical Instrumentation Engineers, v. 17, n. 11, 7 p., 2012.
dc.identifier.doi10.1117/1.JBO.17.11.115004
dc.identifier.issn1083-3668
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/35491
dc.identifier.wosWOS:000314502700011
dc.language.isoeng
dc.publisherSpie-soc Photo-optical Instrumentation Engineers
dc.relation.ispartofJournal of Biomedical Optics
dc.rightsAcesso restrito
dc.subjectZ-scanen
dc.subjectnonlinearen
dc.subjectatherosclerosisen
dc.subjectinflammationen
dc.subjectoral healthen
dc.subjectoxLDLen
dc.subjectperiodontitisen
dc.titleMeasurement of the nonlinear optical response of low-density lipoprotein solutions from patients with periodontitis before and after periodontal treatment: evaluation of cardiovascular risk markersen
dc.typeArtigo
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