Kinetic Modeling of Ethanol Production by Scheffersomyces stipitis from Xylose

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dc.contributor.authorFarias, Daniele
dc.contributor.authorAndrade, Rafael R. de [UNIFESP]
dc.contributor.authorMaugeri-Filho, Francisco
dc.contributor.institutionUniversidade Estadual de Campinas (UNICAMP)
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.date.accessioned2016-01-24T14:35:02Z
dc.date.available2016-01-24T14:35:02Z
dc.date.issued2014-01-01
dc.description.abstractThis work focuses on the kinetics of ethanol production by Scheffersomyces stipitis on xylose with the development of a mathematical model considering the effect of substrate and product concentrations on growth rate. Experiments were carried out in batch and continuous modes, with substrate concentration varying from 7.2 to 145 g L-1. Inhibitory effects on cell growth, substrate uptake, and ethanol production rates were found to be considerable. Kinetic parameters were obtained through linear and non-linear regression methods. Experiments in continuous mode were performed at different dilution rates to evaluate the inhibitory effect of ethanol. A mixed mathematical model which combined Andrews and Levenspiel's models, combining substrate and product inhibition, was used. A quasi-Newton routine was applied to obtain a more accurate fitting of kinetic parameters. the parameters such as cell to product factor (Y (P/X)) and limiting cell yield (Y (X)) were shown to be dependent on substrate concentration. the kinetic model fitted satisfactorily the experimental data.en
dc.description.affiliationUniv Estadual Campinas, Sch Food Engn, BR-13083862 Campinas, SP, Brazil
dc.description.affiliationUniversidade Federal de São Paulo, UNIFESP, Dept Exact & Earth Sci, São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, UNIFESP, Dept Exact & Earth Sci, São Paulo, Brazil
dc.description.sourceWeb of Science
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.format.extent361-379
dc.identifierhttp://dx.doi.org/10.1007/s12010-013-0546-y
dc.identifier.citationApplied Biochemistry and Biotechnology. Totowa: Humana Press Inc, v. 172, n. 1, p. 361-379, 2014.
dc.identifier.doi10.1007/s12010-013-0546-y
dc.identifier.issn0273-2289
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/37231
dc.identifier.wosWOS:000331005200031
dc.language.isoeng
dc.publisherHumana Press Inc
dc.relation.ispartofApplied Biochemistry and Biotechnology
dc.rightsAcesso restrito
dc.subjectEthanol fermentationen
dc.subjectScheffersomyces stipitisen
dc.subjectKinetic parameter estimationen
dc.subjectMathematical modelingen
dc.titleKinetic Modeling of Ethanol Production by Scheffersomyces stipitis from Xyloseen
dc.typeArtigo
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