Synthesis of Silylbiaryl Triflates by Chemoselective Suzuki Reaction

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dc.citation.issue5
dc.citation.volume49
dc.contributor.authorMoreira, Barbara V. [UNIFESP]
dc.contributor.authorMuraca, Ana Carolina A. [UNIFESP]
dc.contributor.authorRaminelli, Cristiano [UNIFESP]
dc.coverageStuttgart
dc.date.accessioned2020-07-17T14:02:48Z
dc.date.available2020-07-17T14:02:48Z
dc.date.issued2017
dc.description.abstractA modular approach for the synthesis of functionalized silylbiaryl triflates has been developed. Iodinated silylaryl triflates were prepared via a gram-scale diiodination reaction, followed by a one-flask transformation, in 42-52% overall yield. The iodinated silylaryl triflates were subjected to a novel chemoselective Suzuki reaction with arylboronic acids, using PdCl2(PPh3)(2) as catalyst and K2CO3 as base in THF/H2O (1:1) at 80 degrees C for 24 hours, which afforded silylbiaryl triflates in 47-81% yield.en
dc.description.affiliationUniv Fed Sao Paulo, Inst Ciencias Ambientais Quim & Farmaceut, Rua Prof Artur Riedel 275, BR-09972270 Diadema, SP, Brazil
dc.description.affiliationUnifespUniv Fed Sao Paulo, Inst Ciencias Ambientais Quim & Farmaceut, Rua Prof Artur Riedel 275, BR-09972270 Diadema, SP, Brazil
dc.description.sourceWeb of Science
dc.description.sponsorshipSao Paulo Research Foundation (FAPESP)
dc.description.sponsorshipFAPESP
dc.description.sponsorshipIDFAPESP: 2015/09984-9
dc.format.extent1093-1102
dc.identifierhttp://dx.doi.org/10.1055/s-0036-1588332
dc.identifier.citationSynthesis-Stuttgart. Stuttgart, v. 49, n. 5, p. 1093-1102, 2017.
dc.identifier.doi10.1055/s-0036-1588332
dc.identifier.issn0039-7881
dc.identifier.urihttps://repositorio.unifesp.br/handle/11600/55033
dc.identifier.wosWOS:000398093000020
dc.language.isoeng
dc.publisherGeorg Thieme Verlag Kg
dc.relation.ispartofSynthesis-Stuttgart
dc.rightsAcesso restrito
dc.subjectiodinated silylaryl triflatesen
dc.subjectchemoselective cross-couplingen
dc.subjectSuzuki reactionen
dc.subjectsilylbiaryl triflatesen
dc.subjectbenzyne chemistryen
dc.titleSynthesis of Silylbiaryl Triflates by Chemoselective Suzuki Reactionen
dc.typeArtigo
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