Statins for progression of aortic valve stenosis and the best evidence for making decisions in health care
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Data
2011-01-06
Autores
Thiago, Luciana
Tsuji, Selma Rumiko [UNIFESP]
Atallah, Alvaro Nagib [UNIFESP]
Puga, Maria Eduarda dos Santos [UNIFESP]
Gois, Aecio Flavio Teixeira de [UNIFESP]
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In the Western world, calcified aortic valve stenosis is the most common form of valvular heart disease, affecting up to 3% of adults over the age of 75 years. It is a gradually progressive disease, characterized by a long asymptomatic phase that may last for several decades, followed by a short symptomatic phase associated with severe restriction of the valve orifice. Investigations on treatments for aortic valve stenosis are still in progress. Thus, it is believed that calcification of aortic valve stenosis is similar to the process of atherosclerosis that occurs in coronary artery disease. Recent studies have suggested that cholesterol lowering through the use of station may have a salutary effect on the progression of aortic valve stenosis.
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Sao Paulo Medical Journal. Sao Paulo: Associacao Paulista Medicina, v. 129, n. 1, p. 41-45, 2011.