Discriminative properties and validity of a health status questionnaire in obstructive airway disease patients: the Airway Questionnaire 20

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Data
2007-12-01
Autores
Camelier, Aquiles
Rosa, Fernanda W.
Nascimento, Oliver A. [UNIFESP]
Ferrandes, Ana Luiza G. [UNIFESP]
Jardim, José Roberto [UNIFESP]
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OBJECTIVE: To evaluate the discriminative properties and validity of the Airways Questionnaire 20 (AQ20) in a sample of patients with airway obstruction and to compare its properties with those of the St George's Respiratory Questionnaire (SGRQ) and the Short Form 36 (SF-36).PATIENTS and METHODS: A convenience sample of 47 subjects was recruited from among 61 consecutive patients referred to an outpatient clinic specialized in obstructive airway diseases. All subjects completed the AQ20, SGRQ, and SF-36. Other measures were the baseline dyspnea index (BDI), 6-minute walk test (6MWT) distance, spirometry, results of arterial blood gas analysis, and body mass index.RESULTS: the AQ20 showed very good correlation with the SGRQ total score (rho=0.84, P <.001) and moderate correlation with all SF-36 domains (physical capacity, rho=-0.53; physical functioning, rho=-0.61; bodily pain, rho=-0.55; general health, rho=4.59; vitality, rho=-0.55; social functioning, rho=-0.57; emotional role functioning, rho=-0.51; mental health, rho=-0.61; all P <.001). the BDI and the 6MWT distance were the best predictors of AQ20 score (r(2)=0.31) in the regression model. An area under the receiver operating characteristic curve of 0.91 (P <.001) indicated a high level of accuracy for the AQ20, using the SGRQ as the gold standard.CONCLUSION: This study shows that the AQ20 is an accurate health status questionnaire in patients with moderate-to-severe airway obstruction. It could be an alternative to longer, traditional questionnaires such as the SGRQ.
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Archivos de Bronconeumologia. Barcelona: Ediciones Doyma S/l, v. 43, n. 12, p. 662-668, 2007.
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