Browsing PPG - Química - Ciência e Tecnologia da Sustentabilidade by Submit Date
Now showing items 1-20 of 210
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Síntese e estudo conformacional de algumas arilamidas derivadas de ésteres de l-cisteína, potenciais inibidores de HIV-1 protease
(Universidade Federal de São Paulo, 2016-08-31)AIDS is a disease that challenges public health on a global scale and which results in major problems due to its side effects, once patients submitted to antiretroviral therapies are bound to develop hypertension. In this ...
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Utilização de regeneradores magnetocalóricos em sistema OTEC
(Universidade Federal de São Paulo, 2015-04-03)The aggravation of the energy crisis initiated at the beginning of the years 1970 and the necessity of generation of energy in a clean and sustainable way stimulate the research for technologies using renewable sources ...
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Estudo químico-computacional sobre o mecanismo de formação da ligação amídica catalisada por ZrCl4
(Universidade Federal de São Paulo, 2016-12-13)The ZrCl4-catalyzed direct amide bond formation between non-activated carboxylic acids and amines has been theoretically investigated at DFT/B3LYP level of theory. In addition we have also characterized the uncatalyzed ...
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Degradação da amoxicilina em efluentes simulados da indústria farmacêutica via processos oxidativos avançados
(Universidade Federal de São Paulo, 2016-01-29)Among the emerging pollutants, drugs, particularly antibiotics, have attracted great attention. This is due to the high consumption in human and veterinary medicine, the potential of causing toxicity to living organisms ...
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Estudo do perfil proteômico do tamanduá-mirim (T. tetradactyla)
(Universidade Federal de São Paulo, 2014-12-17)The increase in anthropological impacts led to the decrease of places that were the natural habitat of several species of animals. This occurrence brought a disadvantage to animal life and the conservation of these species. ...
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Desenvolvimento de potenciais agentes leishmanicidas: benzotiazois inibidores de N-miristoiltransferase
(Universidade Federal de São Paulo, 2016-06-17)N-myristoyltransferase is an enzyme responsible for anchoring proteins to the plasma mem- brane through a cotranslational mechanism of lipidation of proteins in eukaryotes. Previous studies have shown the benzothiazolic ...
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Síntese totais convergentes de alcalóides aporfinoides empregando química de benzino
(Universidade Federal de São Paulo, 2014-01-08)The chemistry of benzyne has been successfully employed in several approaches involving the total synthesis of natural products and bioactive substances. Thus, due to the considerable importance of 2-(trimethylsilyl)aryl ...
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Síntese totais de lisicamina e da (+-)-apomorfina via química de benzino
(Universidade Federal de São Paulo, 2016-04-29)The benzyne chemistry have been successfully employed in several approches involving total syntheses of natural products and bioative substances. Thus, due to the considerable importance of 2-(trimethylsilyl)aryl triflates ...
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Conversão do glicerol utilizando catalisadores ácidos
(Universidade Federal de São Paulo, 2013-11-29)The biodiesel has been added at growing percentages to the diesel sold in Brazil since 2008 and it is currently at the rate of 5 % (B5). This percentual increase brings out the need to find new applications for glycerol, ...
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Avaliação do potencial biorredutor dos microrganismos isolados do processo de compostagem do Zoológico de São Paulo e resolução cinética enzimática do 1-tetralol em DMC e líquidos iônicos
(Universidade Federal de São Paulo, 2015-06-18)The biocatalysis application in synthesis of natural products with biological activity has been an important tool in the organic chemistry. In this context, this academic master thesis involved two fronts: i)Bio-reduction ...
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Estudos visando à síntese esterosseletiva da 4-ariltetralona e resolução cinética enzimática do 4-ariltetralol
(Universidade Federal de São Paulo, 2014-06-06)This academic Master involved two different and complementary paths of work: i) the study of biorreduction of 4-aryltetralone (±)-5 and bio-oxidation of 4-aryltetralol (±)-6 with microorganisms; ii) study of Enzymatic ...
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Desenvolvimento de uma membrana de quitosana com propriedades de barreira celular e capacidade de liberação de droga
(Universidade Federal de São Paulo, 2014-03-06)Chitosan is a water-soluble semisynthetic biopolymer with recognized potential application in the medical field because of properties such as bactericidal activity, biocompatibility, drug releasing, among others. Chitosan ...
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Análise química e biológica dos constituintes fixos e voláteis de Casearia sylvestris sw. (Salicaceae)
(Universidade Federal de São Paulo, 2013-10-05)The present work aimed at the isolation of the chemical constituents of C. sylvestris (Salicaceae), as well as evaluating the cytotoxic activity against tumor cell lines and assays for detection of anti-Leishmania activity ...
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Estudo fitoquímico da espécie vegetal Calophyllum brasiliense (Clusiaceae) visando a seleção de compostos com ação antiparasitária e anttumoral
(Universidade Federal de São Paulo, 2015-01-10)This work consists of phytochemical study and evaluation of the biological activity of the methanol extract of the bark of the trunk and essential oils from leaves, twigs and bark of Calophyllum brasiliense (Clusiaceae). ...
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Estudo bioanalítico e proteômico de sarcoma de Hippopotumus amphibius
(Universidade Federal de São Paulo, 2014-10-24)This project aims to analyse the protein profile of a Hippopotamus amphibius' sarcoma. Using proteomic analysis on three tissue samples of an animal that passed away due to the advanced stage of the disease, an origin ...
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Carragenana acilada como remediadora na adsorção de enzimas em filmes de Lagmuir e Langmuir-Blodgett
(Universidade Federal de São Paulo, 2015-12-17)Interactions involving lipids, polysaccharides and enzymes are of great interest in biological levels as well as in numerous industrial applications. In this context, the aim of this study was to evaluate the role of an ...
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Estudo químico e farmacológico das cascas do tronco de Calophyllum brasiliense (Clusiaceae)
(Universidade Federal de São Paulo, 2013-03-05)In the present work, was conducted the chemical study of methanol extract from the stem barks of Calophyllum brasiliense (Clusiaceae). This extract was also evaluated for antiparasitic potential and displayed high ...
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Fotoeletrorredução de CO2 empregando óxidos nanoestruturados
(Universidade Federal de São Paulo, 2016-02-15)The performance of the heterogeneous photocatalysis in wastewater treatment for the removal of organic pollutants, as well as for gaseous emissions, is associated to semiconductor photo-activity. TiO2 is a semiconductor ...
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Avaliação da atividade herbicida e citotóxica de produtos naturais de Pluchea sagitallis (asteraceae) e seus derivados sintéticos
(Universidade Federal de São Paulo, 2016-07-06)In this proposal, the herbicide potential of the substances isolated from extracts of the roots of Pluchea sagittalis (Asteraceae) has been studied, a species collected in the area of the copper department of Mina do ...
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Processos oxidativos avançados aplicados no tratamento de águas de lavagem da indústria farmacêutica
(Universidade Federal de São Paulo, 2016-07-26)The pharmaceutical residues are an emergent class of environmental contaminants extensively used in human and veterinary medicine. The main waste entry route into the environment is the dumping of domestic sewage, treated ...