Browsing PPG - Biologia Química by Issue Date
Now showing items 41-60 of 130
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Efeito do tratamento com Ginkgo biloba sobre a inflamação hipotalâmica presente em ratos com obesidade induzida pela dieta
(Universidade Federal de São Paulo, 2015-11-27)It has been described that treatment with the standardized extract of Ginkgo biloba (EGb) promotes improvement of inflammatory conditions and this effect arises through inhibition of the Toll-like receptors. It is known ...
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Avaliação da atividade biológica de metabólitos de Lippia alba (Verbenaceae), Plectranthus amboinicus e Plectranthus barbatus (Lamiaceae)
(Universidade Federal de São Paulo, 2016-02-19)This study aimed to identify substances with antimicrobial, antiparasitic and antitumor activities of extract and essential oil from the leaves of Lippia alba (Mill.) N.E. Brown and evaluate the antimicrobial and antitumor ...
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Avaliação da degradação de hidrocarbonetos por bactérias provenientes de compostagem
(Universidade Federal de São Paulo, 2016-02-24)Composting is an alternative to convert organic waste into fertilizer which occurs predominantly by the action of microorganisms. Thus, it is expected that microorganisms capable of degrading various compounds inhabit ...
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Identificação e verificação de atividade celulolítica de microrganismos isolados de compostagem
(Universidade Federal de São Paulo, 2016-02-29)The composting process is an effective and economical way of treating organic waste, mainly by microbial decomposition. The Fundação Parque Zoológico de São Paulo (FPZSP) has a compost production unit (UPCO) that takes ...
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Análise dos transportadores Mup1 e Mup3 em Cryptococcus neoformans e sua importância para os fatores de virulência e captação de aminoácidos
(Universidade Federal de São Paulo, 2016-02-29)The increase in immunocompromised population due to invasive medical procedures and AIDS correlates with high incidence of infections, among which stand out those caused by opportunistic fungi. Invasive Fungal Infections ...
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Avaliação dos efeitos dos componentes dos óleos essenciais (timol, carvacrol e p-cimeno) no enfisema pulmonar induzido por instilação de elastase em camundongos
(Universidade Federal de São Paulo, 2016-03-23)Pulmonary emphysema is the most important component of Chronic Obstructive Pulmonary Disease (COPD) and is characterized by destruction of alveolar walls resulting in an enlargement and progressively airflow limitation. ...
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Estudo químico e avaliação da atividade antimicrobiana dos óleos essenciais extraidos das especies Pimenta dioica (Myrtaceae) e Chenopodium ambrosioides (Amaranthaceae)
(Universidade Federal de São Paulo, 2016-04-15)Currently infectious diseases remain one of the most serious public health problems and have caused many deaths. According to OMS, infectious diseases caused 14.7 million deaths in 2001, or 26% of total world mortality. ...
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Expressão de moléculas da matriz extracelular em células endoteliais resistentes ao anoikis
(Universidade Federal de São Paulo, 2016-04-19)The extracellular matrix (ECM) is a structure composed of several macromolecules that are differently distributed among tissues of organisms. The interaction between ECM molecules and receptors present on the cell membrane ...
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A aspartil aminopeptidase APE4 contribui para os atributos de virulência em Cryptococcus neoformans
(Universidade Federal de São Paulo, 2016-05-31)Cryptococcus neoformans is an opportunistic pathogenic fungus of human beings that infects mainly immunocompromised patients. When left untreated can lead to death and due to similarities between fungal cells and animals, ...
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Efeito do tratamento com extrato padronizado de ginkgo biloba sobre o controle central da ingestão alimentar de ratos
(Universidade Federal de São Paulo, 2016-07-29)The central nervous system plays an important role in controlling food intake. Among the various areas of the central nervous system participating in the homesotático control of food intake and energy expenditure, hypothalamic ...
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Papel de NLRP3 no controle da infecção por Trypanosoma cruzi em células gliais
(Universidade Federal de São Paulo, 2016-08-12)Trypanosoma cruzi (T. cruzi) is the etiologic agent of Chagas disease. Although T. cruzi is mainly described by its ability to cause heart and gut pathologies, imunocompromised chagasic individuals frequently present ...
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Caracterização da presença de AKT no núcleo de células de melanoma e identificação de proteínas associadas por espectrometria de massas
(Universidade Federal de São Paulo, 2016-08-16)The serine threonine kinase AKT/PKB is a critical regulator of various essential physiological cellular processes including cell proliferation, survival, motility and size, metabolism and differentiation. Deregulation of ...
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Identificação química e avaliação do potencial antitumoral dos metabólitos especiais de guarea macrophylla ssp.Tuberculata (meliaceae)
(Universidade Federal de São Paulo, 2016-08-24)Currently, several researches in phytochemical screening are associated with the evaluation of biological activities, aiming the isolation and structural characterization of bioactive compounds. In this context, the species ...
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Estudos sobre a interação entre o receptor HER2 e trastuzumabe em filmes de Langmuir e filmes de Langmuir-Blodgett
(Universidade Federal de São Paulo, 2016-08-25)The present work aimed to characterize the interactions between the HER2 receptor and trastuzumab (Tmab) using Langmuir and Langmuir-Blodgett films as biomembrane models. The comprehension of individual interactions of ...
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Efeito do extrato aquoso da bauhinia forficata link na prevenção do diabetes tipo 2 em modelo animal
(Universidade Federal de São Paulo, 2016-09-12)Diabetes mellitus (DM) is a chronic metabolic disease characterized by hyperglicemic and glucose intolerance, affecting about 415 million people in the world. The most common type of DM is the type 2 (T2DM), characterized ...
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Efeito do tratamento com extrato padronizado de Ginkgo biloba (EGb) sobre o estresse oxidativo e o complemento protéico plasmático de ratos com obesidade induzida pela dieta
(Universidade Federal de São Paulo, 2016-11-29)Obesity is a chronic, multifactorial disease with an increasing worldwide incidence which is strongly associated with the development of several metabolic alterations. Ginkgo biloba standardized extract (GbE) is an herbal ...
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Estudo comparativo da preparação de filmes de poliuretano comercial e sua caracterização química via análise térmica, visando sua aplicação como biomaterial
(Universidade Federal de São Paulo, 2017-03-10)Polyurethane (referred to by the acronym PUR) is a polymer comprising a chain of organic units linked by urethane bonds. This material is widely used in rigid and flexible foams, durable elastomers, high performance ...
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Avaliação do potencial hipoglicêmico dos extratos brutos e neolignanas isoladas de Nectandra leucantha (Lauraceae) em células β pancreáticas
(Universidade Federal de São Paulo, 2017-03-17)Diabetes mellitus (DM) is characterized by chronic hyperglycemia and disorders in the metabolism of carbohydrates, proteins and lipids. This disease affects a large number of people in the world, and in Brazil the prevalence ...
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Interação de violaceína com modelos de membranas
(Universidade Federal de São Paulo, 2017-03-28)Violacein is a violet pigment produced by the gram-negative bacterium Chromobacterium violaceum, which exhibits a multiplicity of biological effects, from which we can highlight bactericidal, antitumoral, antihagasic, ...
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Estudo da encapsulação de 2-aminoetanol-dihidrogenofosfato em sílica mesoporosa altamente ordenada SBA-15 e quitosana
(Universidade Federal de São Paulo (UNIFESP), 2017-06-02)The molecule of 2-aminoethanol dihydrogenphosphate (FSF) is popularly known as phosphoethanolamine. This compound is precursor of phosphatidylethanolamine which is the second most abundant lipid in mammals. For many years, ...
