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Title: Intra-articular injection with triamcinolone hexacetonide in patients with rheumatoid arthritis: prospective assessment of goniometry and joint inflammation parameters
Authors: Vilar Furtado, Rita Nely [UNIFESP]
Machado, Flavia Soares [UNIFESP]
da Luz, Karine Rodrigues [UNIFESP]
dos Santos, Marla Francisca [UNIFESP]
Konai, Monique Sayuri [UNIFESP]
Lopes, Roberta Vilela [UNIFESP]
Natour, Jamil [UNIFESP]
Keywords: Rheumatoid arthritis
Intra-articular injections
Issue Date: 2017
Publisher: Elsevier Science Inc
Citation: Revista Brasileira De Reumatologia. New York, v. 57, n. 2, p. 115-121, 2017.
Abstract: Objectives: To evaluate local joint variables after intra-articular injection (IAI) with triamcinolone hexacetonide (HT) in rheumatoid arthritis (RA) patients. Methods: We blindly and prospectively (baseline, 1, 4, 12 and 24 weeks) evaluated metacarpophalangeal (MCP), wrist, elbow, shoulder, knee and ankle joints after HT IAI by the following outcome measures: Visual analogue scale 0-10 cm (VAS) for rest pain (VASR)
VAS for movement pain (VASM)
VAS for joint swelling (VASSw)
flexion (FlexG) and extension (ExtG). Results: 289 patients (635 joints) were studied. VASSw (p < 0,001) and VASR (0,001< p < 0.016) improved from TO to T4, T12 and T24 for all joints. VASM improved from TO-T4 (p < 0.021) for all joints
TO-T12 (p < 0.023) for MCF and knee
TO-T24 (p < 0.019) only for MCF and knee. FlexG improved from TO-T4 (p < 0.001) for all joints
TO-T12 (p < 0.001) and TO-T24 (p < 0.02) only for MCF and knee. ExtG improved from TO-T4 (p < 0.001) for all joints except for elbow
TO-T12 (p = 0.003) for wrist, MCP and knee
and TO-T24 (p = 0.014) for MCF and knee. Conclusion: VASSw responded better at short and medium term after IAI with HT in our sample of RA patients. (C) 2016 Published by Elsevier Editora Ltda.
ISSN: 0482-5004
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