Please use this identifier to cite or link to this item: https://repositorio.unifesp.br/11600/43980
Title: ACUTE EFFECTS ON BONE-MARROW AFTER ASSOCIATION BETWEEN RADIOSENSITIZER AND X-RAYS - NN/N METHOD
Authors: Segreto, Helena Regina Comodo [UNIFESP]
Segreto, Roberto Araujo [UNIFESP]
Thomaz, K.
Silva, MRR
Novo, Neil Ferreira [UNIFESP]
Keywords: IONIZING RADIATION
RADIOSENSITIZERS
ACUTE EFFECTS ON BONE MARROW
Issue Date: 1994-03-01
Publisher: Interciencia
Citation: Interciencia. Caracas: Interciencia, v. 19, n. 2, p. 75-78, 1994.
Abstract: A histopathological and morphometric study was performed in the bone marrow of mice after association of cisdiamminedi-chloroplatinum II (3.0 mg/kg) plus X-rays (103.20 mC/kg - 400R). Estimation of bone marrow effects was assessed by counting the number of non nucleated-erythrocytes (NN) and nucleated (N) cells, and establishing (NN/N) ratio.The morphomeric method used correlates and makes possible quantification of histopathologic changes of bone marrow through relation of vascular stroma and cellular parenchyma. It can be used as a biological dosimetry parameter and to estimate injury and recovery of hematologic evolution of different myelotoxic agents.
URI: http://repositorio.unifesp.br/11600/43980
metadata.dc.language.iso: eng
metadata.dc.rights: Acesso restrito
metadata.dc.type: Artigo
metadata.dc.format.extent: 75-78
Appears in Collections:EPM - Artigos

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