Please use this identifier to cite or link to this item: https://repositorio.unifesp.br/handle/11600/37923
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dc.contributor.authorMiotto e Silva, Vanessa Bugni [UNIFESP]
dc.contributor.authorTavares da Silva, Carolina de Freitas [UNIFESP]
dc.contributor.authorVilela Mitraud, Sonia de Aguiar [UNIFESP]
dc.contributor.authorVilar Furtado, Rita Nely [UNIFESP]
dc.contributor.authorEsteves Hilario, Maria Odete [UNIFESP]
dc.contributor.authorNatour, Jamil [UNIFESP]
dc.contributor.authorTerreri, Maria Teresa [UNIFESP]
dc.date.accessioned2016-01-24T14:37:31Z-
dc.date.available2016-01-24T14:37:31Z-
dc.date.issued2014-07-01
dc.identifierhttp://dx.doi.org/10.1007/s00296-013-2909-7
dc.identifier.citationRheumatology International. Heidelberg: Springer Heidelberg, v. 34, n. 7, p. 937-945, 2014.
dc.identifier.issn0172-8172
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/37923-
dc.description.abstractThe aim of the study was to assess the presence and characteristics of subclinical synovitis using power Doppler (PD) ultrasonography on patients with juvenile idiopathic arthritis (JIA) in clinical remission and compare the findings with those of healthy children. A cross-sectional study was carried out involving the clinical (physical exam, functional capacity and laboratory tests) and ultrasonography evaluation of 34 joints (synovial fluid/hypertrophy, PD signal and bone erosion). Subclinical synovitis was defined as the presence of synovial hypertrophy/joint effusion with or without any PD signal. Thirty-six patients (11.5 +/- A 3.74 years) and 36 controls (sex and age matched) were evaluated (2,448 joints). Twenty-seven patients were in remission on medication (mean duration: 1.8 +/- A 2.2 years). Subclinical synovitis was detected in 41.7 % patients and 11.1 % controls (p = 0.003). Erosion was detected in three patients (8.3 %). Subclinical synovitis was found in 38/1,224 (3.1 %) joints in the patients (most affected: radiocarpal wrist, anterior elbow and tibiotalar ankle) and 8/1,224 (0.6 %) joints in the controls (most affected: radiocarpal wrist). Differences in subclinical synovitis between patients and controls were found in the elbows (p = 0.033) and ankles (p = 0.006). A greater frequency of subclinical synovitis was found in patients with the extended oligoarticular or polyarticular subtypes (p = 0.013), those at an older age at disease onset (p = 0.007) and using methotrexate (p = 0.049). Patients with JIA in remission exhibit subclinical synovitis more frequently than controls. Subclinical synovitis was more frequent in patients with the polyarticular involvement and those at an older age at disease onset.en
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.format.extent937-945
dc.language.isoeng
dc.publisherSpringer
dc.relation.ispartofRheumatology International
dc.rightsAcesso restrito
dc.subjectJuvenile idiopathic arthritisen
dc.subjectSynovitisen
dc.subjectDoppler ultrasounden
dc.subjectChilden
dc.subjectRemission inductionen
dc.titleDo patients with juvenile idiopathic arthritis in remission exhibit active synovitis on joint ultrasound?en
dc.typeArtigo
dc.rights.licensehttp://www.springer.com/open+access/authors+rights?SGWID=0-176704-12-683201-0
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.description.affiliationUniversidade Federal de São Paulo, Escola Paulista Med UNIFESP EPM, Dept Pediat, Pediat Rheumatol Unit,Allergy Immunol & Rheumatol, BR-04022005 São Paulo, Brazil
dc.description.affiliationUniversidade Federal de São Paulo, Escola Paulista Med UNIFESP EPM, BR-04022005 São Paulo, Brazil
dc.description.affiliationUniversidade Federal de São Paulo, Escola Paulista Med UNIFESP EPM, Dept Diagnost Imaging, BR-04022005 São Paulo, Brazil
dc.description.affiliationUniversidade Federal de São Paulo, Escola Paulista Med UNIFESP EPM, Dept Med, Div Rheumatol, BR-04022005 São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Escola Paulista Med UNIFESP EPM, Dept Pediat, Pediat Rheumatol Unit,Allergy Immunol & Rheumatol, BR-04022005 São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Escola Paulista Med UNIFESP EPM, BR-04022005 São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Escola Paulista Med UNIFESP EPM, Dept Diagnost Imaging, BR-04022005 São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Escola Paulista Med UNIFESP EPM, Dept Med, Div Rheumatol, BR-04022005 São Paulo, Brazil
dc.description.sponsorshipIDFAPESP: 2010/50128-5
dc.identifier.doi10.1007/s00296-013-2909-7
dc.description.sourceWeb of Science
dc.identifier.wosWOS:000338332300006
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