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Title: Biomechanical properties: effects of low-level laser therapy and Biosilicate (R) on tibial bone defects in osteopenic rats
Authors: Fangel, Renan
Bossini, Paulo Sergio
Renno, Ana Claudia Muniz [UNIFESP]
Granito, Renata Neves
Wang, Charles Chenwei
Nonaka, Keico Okino
Driusso, Patricia
Parizotto, Nivaldo Antonio
Oishi, Jorge
Keywords: Biomaterial
Biomechanical properties
Bone healing
Low-level laser therapy
Issue Date: 2014-01-01
Publisher: Wichtig Editore
Citation: Journal of Applied Biomaterials & Functional Materials. Milan: Wichtig Editore, v. 12, n. 3, p. 271-277, 2014.
Abstract: Purpose: the aim of this study was to investigate the effects of laser therapy and Biosilicate (R) on the biomechanical properties of bone callus in osteopenic rats.Methods: Fifty female Wistar rats were equally divided into 5 groups (n=10/group): osteopenic rats with intact tibiae (SC); osteopenic rats with unfilled and untreated tibial bone defects (OC); osteopenic rats whose bone defects were treated with Biosilicate (R) (B); osteopenic rats whose bone defects were treated with 830-nm laser, at 120 J/cm(2) (L120) and osteopenic rats whose bone defects were treated with Biosilicate (R) and 830-nm laser, at 120 J/cm(2) (BL120). Ovariectomy (OVX) was used to induce osteopenia. A non-critical bone defect was created on the tibia of the osteopenic animals 8 weeks after OVX. in Biosilicate (R) groups, bone defects were completely filled with the biomaterial. for the laser therapy, an 830-nm laser, 120 J/cm(2) was used. On day 14 postsurgery, rats were euthanized, and tibiae were removed for biomechanical analysis.Results: Maximal load and energy absorption were higher in groups B and BL120, according to the indentation test. Animals submitted to low-level laser therapy (LLLT) did not show any significant biomechanical improvement, but the association between Biosilicate (R) and LLLT was shown to be efficient to enhance callus biomechanical properties. Conversely, no differences were found between study groups in the bending test.Conclusions: Biosilicate (R) alone or in association with low level laser therapy improves biomechanical properties of tibial bone callus in osteopenic rats.
metadata.dc.language.iso: eng
Other Identifiers:
metadata.dc.rights: Acesso restrito
metadata.dc.type: Artigo
metadata.dc.format.extent: 271-277
Appears in Collections:ISS - Artigos

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