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Title: Prognostic value of regional metastasis in squamous cell carcinoma of the tongue and floor of mouth
Other Titles: Valor prognóstico da metástase regional no carcinoma epidermoide de língua e soalho bucal
Authors: Amar, Ali [UNIFESP]
Rapoport, Abrao
Curioni, Otavio Alberto
Dedivitis, Rogerio Aparecido
Cernea, Claudio Roberto
Brandao, Lenine Garcia
Universidade Federal de São Paulo (UNIFESP)
Heliopolis Hosp
Universidade de São Paulo (USP)
Sao Jose Hosp
Keywords: carcinoma, squamous cell
lymphatic metastasis
mouth neoplasms
Issue Date: 1-Nov-2013
Publisher: Assoc Brasileira Otorrinolaringologia & Cirurgia Cervicofacial
Citation: Brazilian Journal of Otorhinolaryngology. São Paulo: Assoc Brasileira Otorrinolaringologia & Cirurgia Cervicofacial, v. 79, n. 6, p. 734-737, 2013.
Abstract: The presence of metastatic nodes is a survival-limiting factor for patients with mouth tumors.Objective: To evaluate the causes of treatment failure in carcinomas of the tongue and floor of the mouth due to staging.Method: This study included 365 patients with squamous cell carcinoma of the mouth treated from 1978 to 2007; 48 were staged as T1, 156 as T2, 98 as T3, and 63 as T4, of which 193 were pNo and 172 pN+.Results: Among the pN+ cases, 17/46 (36.9%) of the patients not treated with radiation therapy had relapsing tumors, against 46/126 (36.5 %) of the patients who underwent radiation therapy. Success rates in the group of subjects submitted to salvage procedures were 16/51 (31.3%) for pN0 patients and 3/77 (3.9%) for pN+ patients.Conclusion: Salvage procedure success and survival rates are lower for pN+ patients; pN+ individuals also have more relapsing local disease.
ISSN: 1808-8694
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