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Title: How to invade, replicate, and escape from host organisms. A challenge in defining virulence factors for parasites
Authors: Schenkman, Sergio [UNIFESP]
Gonzalez, Jorge
Universidade Federal de São Paulo (UNIFESP)
5 Univ Antofagasta
Issue Date: 1-Dec-2012
Publisher: Elsevier B.V.
Citation: Microbes and Infection. Amsterdam: Elsevier B.V., v. 14, n. 15, p. 1374-1376, 2012.
Abstract: During millions of years, parasites have been adapting to different environments and hosts. During this time, they have acquired different molecules and peculiar structures, some absent in other living organisms, in order to successfully invade hosts, resist immune attack, and proliferate in the hosts. Nowadays, several genome sequences and a multitude of new information have been generated for many human and animal parasites, opening new possibilities for understanding in detail how they interact with the host and cause disease. Investigations of these molecules and the associated structures, together with their functional roles, are now emerging, providing key advances in understanding pathology that could be used for developing robust strategies to selectively target the parasites without damaging the host. (C) 2012 Institut Pasteur. Published by Elsevier Masson SAS. All rights reserved.
ISSN: 1286-4579
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Appears in Collections:Em verificação - Geral

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