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Title: Tumor neuroectodérmico primitivo supratentorial: estudo de quatro casos
Other Titles: Primitive neuroectodermal tumor of the central nervous system: report of four cases
Authors: Minett, Thaís Soares Cianciarullo [UNIFESP]
Neves, Beatrice Maria J. [UNIFESP]
Stávale, João Norberto [UNIFESP]
Universidade Federal de São Paulo (UNIFESP)
Keywords: primitive neuroectodermal tumor
tumor neuroectodérmico primitivo
Issue Date: 1-Sep-1994
Publisher: Academia Brasileira de Neurologia - ABNEURO
Citation: Arquivos de Neuro-Psiquiatria. Academia Brasileira de Neurologia - ABNEURO, v. 52, n. 3, p. 392-395, 1994.
Abstract: The clinicopathological and immunohistochemical features of four cases of primitive neuroectodermal tumors of the central nervous system were investigated. Three patients died. All cases showed vimentin-positive cells with the morphology of neoplastic cells and one case showed glial fibrillary acidic protein, neuron-specific enolase and neurofilament protein-positive cell. The present study indicates that this group of tumors have bad prognostics and may show immunocytochemical features indicating glial and/or neuronal differentiation.
As alterações clinicopatológicas e imuno-histoquímicas de quatro casos de tumores neuroectodérmicos primitivos do sistema nervoso central foram investigadas. Três pacientes morreram. Todos os casos mostraram células vimentina positivas com morfologia de células neoplásicas e um caso mostrou células neoplásicas com imunoexpressão para proteína glial fibrilar acídica, enolase neuro-específica e neurofilamento. O presente estudo indica que este grupo de tumores tem mau prognóstico e pode mostrar alterações imuno-histoquímicas que indicam diferenciação glial e/ou neuronal.
ISSN: 0004-282X
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