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Title: Reversed Halo Sign High-Resolution CT Scan Findings in 79 Patients
Authors: Marchiori, Edson
Zanetti, Glaucia
Escuissato, Dante Luiz
Souza, Arthur Soares
Meirelles, Gustavo de Souza Portes [UNIFESP]
Fagundes, Joana
Souza, Carolina Althoff
Hochhegger, Bruno
Marom, Edith M.
Godoy, Myrna C. B.
Universidade Federal do Rio de Janeiro (UFRJ)
Univ Fed Parana
Universidade de São Paulo (USP)
Universidade Federal de São Paulo (UNIFESP)
Ottawa Hosp
Univ Texas MD Anderson Canc Ctr
Issue Date: 1-May-2012
Publisher: Amer Coll Chest Physicians
Citation: Chest. Northbrook: Amer Coll Chest Physicians, v. 141, n. 5, p. 1260-1266, 2012.
Abstract: Background: the purpose of this study was to evaluate the high-resolution CT (HRCT) scan findings of patients with the reversed halo sign (RHS) and to identify distinguishing features among the various causes.Methods: Two chest radiologists reviewed the HRCT scans of 79 patients with RHS and determined the CT scan findings by consensus. We studied the morphologic characteristics, number of lesions, and presence of features associated with RHS.Results: Forty-one patients presented with infectious diseases (paracoccidioidomycosis, TB, zygomycosis, invasive pulmonary aspergillosis, Pneumocystis jiroveci pneumonia, histoplasmosis, cryptococcosis), and 38 presented with noninfectious diseases (cryptogenic organizing pneumonia, pulmonary embolism, sarcoidosis, edema, lepidic predominant adenocarcinoma [formerly bronehiolo-alveolar carcinoma], granulomatosis with polyangiitis [Wegener]). the RHS walls were smooth in 58 patients (73.4%) and nodular in 21 patients (26.6%). Lesions were multiple in 40 patients (50.6%) and single in 39 patients (49.4%).Conclusion: the presence of nodular walls or nodules inside the halo of the RHS is highly suggestive of granulomatous diseases. CHEST 2012; 141(5):1260-1266
ISSN: 0012-3692
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