Please use this identifier to cite or link to this item: https://repositorio.unifesp.br/handle/11600/34656
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dc.contributor.authorDattilo, Murilo [UNIFESP]
dc.contributor.authorAntunes, Hanna Karen Moreira [UNIFESP]
dc.contributor.authorMedeiros, Alessandra [UNIFESP]
dc.contributor.authorMônico-Neto, Marcos [UNIFESP]
dc.contributor.authorSouza, Helton de Sá
dc.contributor.authorLee, Kil Sun [UNIFESP]
dc.contributor.authorTufik, Sergio [UNIFESP]
dc.contributor.authorMello, Marco Tulio de [UNIFESP]
dc.date.accessioned2016-01-24T14:26:52Z
dc.date.available2016-01-24T14:26:52Z
dc.date.issued2012-03-01
dc.identifierhttp://dx.doi.org/10.1002/mus.22322
dc.identifier.citationMuscle & Nerve. Malden: Wiley-Blackwell, v. 45, n. 3, p. 431-433, 2012.
dc.identifier.issn0148-639X
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/34656
dc.description.abstractIntroduction: Because paradoxical sleep deprivation (PSD) induces a catabolic hormone profile, we sought to evaluate the morphology of the tibialis anterior (TA) muscle and testosterone and corticosterone levels of paradoxical sleepdeprived rats.Methods: Three study groups of rats were established: the first group was sleep deprived for 96 h; the second group was also sleep deprived for 96 h, but then returned to their home-cage and allowed to sleep for the next 96 h; and the third group was the control group, with a normal sleep cycle. Results: PSD reduced the weight and fiber cross-sectional area of the TA muscle. Moreover, PSD enhanced plasma corticosterone and reduced serum testosterone levels. the 96 h of sleep after PSD was sufficient to restore partially the morphology of TA, while hormones returned to basal levels. Conclusion: PSD induces hormonal alterations that may mediate muscle atrophy. Muscle Nerve, 2012en
dc.description.sponsorshipAssociacao Fundo de Incentivo a Pesquisa (AFIP)
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.description.sponsorshipCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
dc.description.sponsorshipUniversidade Federal de São Paulo (UNIFESP)
dc.description.sponsorshipFundo de Auxllio aos Docentes e Alunos (FADA)
dc.format.extent431-433
dc.language.isoeng
dc.publisherWiley-Blackwell
dc.relation.ispartofMuscle & Nerve
dc.rightsAcesso restrito
dc.subjectcross-sectional areaen
dc.subjectcorticosteroneen
dc.subjectmuscle atrophyen
dc.subjectparadoxical sleep deprivationen
dc.subjecttestosteroneen
dc.titleParadoxical sleep deprivation induces muscle atrophyen
dc.typeArtigo
dc.rights.licensehttp://olabout.wiley.com/WileyCDA/Section/id-406071.html
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.contributor.institutionCEPE
dc.description.affiliationUniversidade Federal de São Paulo, Dept Psicobiol, BR-04020050 São Paulo, Brazil
dc.description.affiliationUniversidade Federal de São Paulo, Dept Biociencias, Santos, Brazil
dc.description.affiliationCEPE, São Paulo, Brazil
dc.description.affiliationUniversidade Federal de São Paulo, Dept Bioquim, BR-04020050 São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Dept Psicobiol, BR-04020050 São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Dept Biociencias, Santos, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Dept Bioquim, BR-04020050 São Paulo, Brazil
dc.description.sponsorshipIDFAPESP: 2009/11056-1
dc.description.sponsorshipIDFAPESP: 98/14303-3
dc.identifier.doi10.1002/mus.22322
dc.description.sourceWeb of Science
dc.identifier.wosWOS:000300684600017
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