Now showing items 1-6 of 6

    • Hippocampal volume and the rapid antidepressant effect of ketamine 

      Abdallah, Chadi G.; Salas, Ramiro; Jackowski, Andrea [UNIFESP]; Baldwin, Philip; Sato, Joao R. [UNIFESP]; Mathew, Sanjay J. (Sage Publications Ltd, 2015-05-01)
      Accumulating evidence underscores the utility of ketamine in treating severely treatment-resistant depressed patients. We investigated the relationship between the rapid antidepressant effects of ketamine and hippocampal ...
    • The Nucleus Accumbens and Ketamine Treatment in Major Depressive Disorder 

      Abdallah, Chadi G.; Jackowski, Andrea [UNIFESP]; Salas, Ramiro; Gupta, Swapnil; Sato, Joao R. [UNIFESP]; Mao, Xiangling; Coplan, Jeremy D.; Shungu, Dikoma C.; Mathew, Sanjay J. (Nature Publishing Group, 2017)
      Animal models of depression repeatedly showed stress-induced nucleus accumbens (NAc) hypertrophy. Recently, ketamine was found to normalize this stress-induced NAc structural growth. Here, we investigated NAc structural ...
    • A pilot study of hippocampal volume and N-acetylaspartate (NAA) as response biomarkers in riluzole-treated patients with GAD 

      Abdallah, Chadi G.; Coplan, Jeremy D.; Jackowski, Andrea [UNIFESP]; Sato, Joao R. [UNIFESP]; Mao, Xiangling; Shungu, Dikoma C.; Mathew, Sanjay J. (Elsevier B.V., 2013-04-01)
      Anxiolytic benefit following chronic treatment with the glutamate modulating agent riluzole in patients with generalized anxiety disorder (GAD) was previously associated with differential changes in hippocampal NAA ...
    • PRODH Polymorphisms, Cortical Volumes and Thickness in Schizophrenia 

      Ota, Vanessa Kiyomi Arashiro [UNIFESP]; Bellucco, Fernanda Teixeira da Silva [UNIFESP]; Gadelha, Ary [UNIFESP]; Santoro, Marcos Leite [UNIFESP]; Noto, Cristiano [UNIFESP]; Christofolini, Denise Maria; Assunção, Idaiane Batista de [UNIFESP]; Yamada, Karen M. [UNIFESP]; Ribeiro-dos-Santos, Andrea K.; Santos, Sidney; Mari, Jair de Jesus [UNIFESP]; Smith, Marilia de Arruda Cardoso [UNIFESP]; Melaragno, Maria I. [UNIFESP]; Bressan, Rodrigo Affonseca [UNIFESP]; Sato, Joao R. [UNIFESP]; Jackowski, Andrea Parolin [UNIFESP]; Belangero, Sintia Iole [UNIFESP] (Public Library Science, 2014-02-03)
      Schizophrenia is a neurodevelopmental disorder with high heritability. Several lines of evidence indicate that the PRODH gene may be related to the disorder. Therefore, our study investigates the effects of 12 polymorphisms ...
    • Riluzole effect on occipital cortex: A structural and spectroscopy pilot study 

      Abdallah, Chadi G.; Coplan, Jeremy D.; Jackowski, Andrea [UNIFESP]; Sato, Joao R. [UNIFESP]; Mao, Xiangling; Shungu, Dikoma C.; Mathew, Sanjay J. (Elsevier B.V., 2012-11-14)
      Background: To investigate the mechanism underlying the anxiolytic properties of riluzole, a glutamate-modulating agent, we previously studied the effect of this drug on hippocampal N-acetylaspartate (NAA) and volume in ...
    • Ventral Striatum Functional Connectivity as a Predictor of Adolescent Depressive Disorder in a Longitudinal Community-Based Sample 

      Pan, Pedro Mario [UNIFESP]; Sato, Joao R. [UNIFESP]; Salum, Giovanni A.; Rohde, Luis A.; Gadelha, Ary [UNIFESP]; Zugman, Andre [UNIFESP]; Mari, Jair [UNIFESP]; Jackowski, Andrea [UNIFESP]; Picon, Felipe; Miguel, Euripedes C.; Pine, Daniel S.; Leibenluft, Ellen; Bressan, Rodrigo A. [UNIFESP]; Stringaris, Argyris (Amer Psychiatric Publishing, Inc, 2017)
      Objective: Previous studies have implicated aberrant reward processing in the pathogenesis of adolescent depression. However, no study has used functional connectivity within a distributed reward network, assessed using ...