Now showing items 1-20 of 34

    • Alcohol use disorders in patients with obsessive-compulsive disorder: the importance of appropriate dual-diagnosis 

      Gentil, Andre F.; Mathis, Maria Alice de; Torresan, Ricardo C.; Diniz, Juliana B.; Alvarengat, Pedro; Rosario, Maria Conceicao do [UNIFESP]; Cordioli, Aristides V.; Torres, Albina R.; Miguel, Euripedes C. (Elsevier B.V., 2009-02-01)
      Objective: To evaluate the prevalence and clinical associated factors of alcohol use disorders (AUD) comorbidity in a large clinical sample of patients with obsessive-compulsive disorder (OCD).Methods: A cross-sectional ...
    • Association of serum interleukin-6 with mental health problems in children exposed to perinatal complications and social disadvantage 

      Mansur, Rodrigo B. [UNIFESP]; Cunha, Graccielle R. [UNIFESP]; Asevedo, Elson [UNIFESP]; Zugman, Andre [UNIFESP]; Rizzo, Lucas B. [UNIFESP]; Grassi-Oliveira, Rodrigo; Levandowski, Mateus L.; Gadelha, Ary [UNIFESP]; Pan, Pedro M. [UNIFESP]; Teixeira, Antonio L.; McIntyre, Roger S.; Mari, Jair J. [UNIFESP]; Rohde, Luis A.; Miguel, Euripedes C.; Bressan, Rodrigo A. [UNIFESP]; Brietzke, Elisa [UNIFESP] (Pergamon-Elsevier Science Ltd, 2016)
      There is consistent evidence that inflammation is involved in mental disorders pathogenesis. Herein, using data from the High Risk Cohort Study for Psychiatric Disorders, we investigated the relationship between parental ...
    • Clinical features of obsessive-compulsive disorder with hoarding symptoms: A multicenter study 

      Torres, Albina R.; Fontenelle, Leonardo F.; Ferrao, Ygor A.; Rosario, Maria Conceicao do [UNIFESP]; Torresan, Ricardo C.; Miguel, Euripedes C.; Shavitt, Roseli G. (Elsevier B.V., 2012-06-01)
      Background: Factor analyses indicate that hoarding symptoms constitute a distinctive dimension of obsessive-compulsive disorder (OCD), usually associated with higher severity and limited insight. the aim was to compare ...
    • Cognitive dysfunction in post-traumatic obsessive-compulsive disorder 

      Borges, Manuela C.; Braga, Daniela T.; Iego, Sandro; D'Alcante, Carina C.; Sidrim, Ilduara; Machado, Maria Cristiana; Pinto, Paula S. P.; Cordioli, Aristides V.; Rosario, Maria Conceicao do [UNIFESP]; Petribu, Katia; Mendlowicz, Mauro V.; Mari, Jair J. [UNIFESP]; Miguel, Euripedes C.; Fontenelle, Leonardo F. (Informa Healthcare, 2011-01-01)
      Objective: To investigate whether patients who develop obsessive-compulsive disorder (OCD) after posttraumatic stress disorder, i.e. post-traumatic OCD (PsT-OCD), display a distinctive neurocognitive pattern of ...
    • Comorbid major depression in obsessive-compulsive disorder patients 

      Quarantini, Lucas C.; Torres, Albina Rodrigues; Sampaio, Aline S.; Fossaluza, Victor; Mathis, Maria Alice de; Rosario, Maria Conceicao do [UNIFESP]; Fontenelle, Leonardo F.; Ferrao, Ygor A.; Cordioli, Aristides Volpato; Petribu, Katia; Hounie, Ana G.; Miguel, Euripedes C.; Shavitt, Roseli G.; Koenen, Karestan C. (Elsevier B.V., 2011-07-01)
      Although major depressive disorder (MDD) has been consistently considered the most frequent complication of obsessive-compulsive disorder (OCD), little is known about the clinical characteristics of patients with both ...
    • Copy Number Variation in Obsessive-Compulsive Disorder and Tourette Syndrome: A Cross-Disorder Study 

      McGrath, Lauren M.; Yu, Dongmei; Marshall, Christian; Davis, Lea K.; Thiruvahindrapuram, Bhooma; Li, Bingbin; Cappi, Carolina; Gerber, Gloria; Wolf, Aaron; Schroeder, Frederick A.; Osiecki, Lisa; O'Dushlaine, Colm; Kirby, Andrew; Illmann, Cornelia; Haddad, Stephen; Gallagher, Patience; Fagerness, Jesen A.; Barr, Cathy L.; Bellodi, Laura; Benarroch, Fortu; Bienvenu, O. Joseph; Black, Donald W.; Bloch, Michael H.; Bruun, Ruth D.; Budman, Cathy L.; Camarena, Beatriz; Cath, Danielle C.; Cavallini, Maria C.; Chouinard, Sylvain; Coric, Vladimir; Cullen, Bernadette; Delorme, Richard; Denys, Damiaan; Derks, Eske M.; Dion, Yves; Rosario, Maria C.; Eapen, Valsama; Evans, Patrick; Falkai, Peter; Fernandez, Thomas V.; Garrido, Helena; Geller, Daniel; Grabe, Hans J.; Grados, Marco A.; Greenberg, Benjamin D.; Gross-Tsur, Varda; Gruenblatt, Edna; Heiman, Gary A.; Hemmings, Sian M. J.; Herrera, Luis D.; Hounie, Ana G.; Jankovic, Joseph; Kennedy, James L.; King, Robert A.; Kurlan, Roger; Lanzagorta, Nuria; Leboyer, Marion; Leckman, James F.; Lennertz, Leonhard; Lochner, Christine; Lowe, Thomas L.; Lyon, Gholson J.; Macciardi, Fabio; Maier, Wolfgang; McCracken, James T.; McMahon, William; Murphy, Dennis L.; Naarden, Allan L.; Neale, Benjamin M.; Nurmi, Erika; Pakstis, Andrew J.; Pato, Michele T.; Pato, Carlos N.; Piacentini, John; Pittenger, Christopher; Pollak, Yehuda; Reus, Victor I.; Richter, Margaret A.; Riddle, Mark; Robertson, Mary M.; Rosenberg, David; Rouleau, Guy A.; Ruhrmann, Stephan; Sampaio, Aline S. [UNIFESP]; Samuels, Jack; Sandor, Paul; Sheppard, Brooke; Singer, Harvey S.; Smit, Jan H.; Stein, Dan J.; Tischrield, Jay A.; Vallada, Homero; Veenstra-VanderWeele, Jeremy; Walitza, Susanne; Wang, Ying; Wendfand, Jens R.; Shugart, Yin Yao; Miguel, Euripedes C.; Nicolini, Humberto; Oostra, Ben A.; Moessner, Rainald; Wagner, Michael; Ruiz-Linares, Andres; Heutink, Peter; Nestadt, Gerald; Freimer, Nelson; Petryshen, Tracey; Posthuma, Danielle; Jenike, Michael A.; Cox, Nancy J.; Hanna, Gregory L.; Brentani, Helena; Scherer, Stephen W.; Arnold, Paul D.; Stewart, S. Evelyn; Mathews, Carol A.; Knowles, James A.; Cook, Edwin H.; Pauls, David L.; Wang, Kai; Scharf, Jeremiah M. (Elsevier B.V., 2014-08-01)
      Objective: Obsessive-compulsive disorder (OCD) and Tourette syndrome (TS) are heritable neurodevelopmental disorders with a partially shared genetic etiology. This study represents the first genome-wide investigation of ...
    • Cross-Disorder Genome-Wide Analyses Suggest a Complex Genetic Relationship Between Tourette's Syndrome and OCD 

      Yu, Dongmei; Mathews, Carol A.; Scharf, Jeremiah M.; Neale, Benjamin M.; Davis, Lea K.; Gamazon, Eric R.; Derks, Eske M.; Evans, Patrick; Edlund, Christopher K.; Crane, Jacquelyn; Osiecki, Lisa; Gallagher, Patience; Gerber, Gloria; Haddad, Stephen; Illmann, Cornelia; McGrath, Lauren M.; Mayerfeld, Catherine; Arepalli, Sampath; Barlassina, Cristina; Barr, Cathy L.; Bellodi, Laura; Benarroch, Fortu; Berrio, Gabriel Bedoya; Bienvenu, O. Joseph; Black, Donald W.; Bloch, Michael H.; Brentani, Helena; Bruun, Ruth D.; Budman, Cathy L.; Camarena, Beatriz; Campbell, Desmond D.; Cappi, Carolina; Silgado, Julio C. Cardona; Cavallini, Maria C.; Chavira, Denise A.; Chouinard, Sylvain; Cook, Edwin H.; Cookson, M. R.; Coric, Vladimir; Cullen, Bernadette; Cusi, Daniete; Delorme, Richard; Denys, Damiaan; Dion, Yves; Eapen, Valsama; Egberts, Karin; Falkai, Peter; Fernandez, Thomas; Fournier, Eduardo; Garrido, Helena; Geller, Daniel; Gilbert, Donald L.; Girard, Simon L.; Grabe, Hans J.; Grados, Marco A.; Greenberg, Benjamin D.; Gross-Tsur, Varda; Gruenblatt, Edna; Hardy, John; Heiman, Gary A.; Hemmings, Sian M. J.; Herrera, Luis D.; Hezel, Dianne M.; Hoekstra, Pieter J.; Jankovic, Joseph; Kennedy, James L.; King, Robert A.; Konkashbaev, Anuar I.; Kremeyer, Barbara; Kurlan, Roger; Lanzagorta, Nuria; Leboyer, Marion; Leckman, James F.; Lennertz, Leonhard; Liu, Chunyu; Lochner, Christine; Lowe, Thomas L.; Lupoli, Sara; Macciardi, Fabio; Maier, Wolfgang; Manunta, Paolo; Marconi, Maurizio; McCracken, James T.; Restrepo, Sandra C. Mesa; Moessner, Rainald; Moorjani, Priya; Morgan, Jubel; Muller, Heike; Murphy, Dennis L.; Naarden, Allan L.; Nurmi, Erika; Ochoa, William Cornejo; Ophoff, Roel A.; Pakstis, Andrew J.; Pato, Michele T.; Pato, Carlo N.; Piacentini, John; Pittenger, Christopher; Pollak, Yehuda; Rauch, Scott L.; Renner, Tobias; Reus, Victor I.; Richter, Margaret A.; Riddle, Mark A.; Robertson, Mary M.; Romero, Roxana; Rosario, Maria C.; Rosenberg, David; Ruhrmann, Stephan; Sabatti, Chiara; Salvi, Erika; Sampaio, Aline S.; Samuels, Jack; Sandor, Paul; Service, Susan K.; Sheppard, Brooke; Singer, Harvey S.; Smit, Jan H.; Stein, Dan J.; Strengman, Eric; Tischfield, Jay A.; Turiel, Maurizio; Duarte, Ana V. Valencia; Vallada, Homero; Veenstra-VanderWeele, Jeremy; Walitza, Susanne; Wang, Ying; Weale, Mike; Weiss, Robert; Wendland, Jens R.; Westenberg, Herman G. M.; Shugart, Yin Yao; Hounie, Ana G.; Miguel, Euripedes C.; Nicolini, Humberto; Wagner, Michael; Ruiz-Linares, Andres; Cath, Danielle C.; McMahon, William; Posthuma, Danielle; Oostra, Ben A.; Nestadt, Gerald; Routeau, Guy A.; Purcell, Shaun; Jenike, Michael A.; Heutink, Peter; Hanna, Gregory L.; Conti, David V.; Arnold, Paul D.; Freimer, Nelson B.; Stewart, Evelyn; Knowles, James A.; Cox, Nancy J.; Pauls, David L. (Amer Psychiatric Publishing, Inc, 2015-01-01)
      Objective: Obsessive-compulsive disorder (OCD) and Tourette's syndrome are highly heritable neurodevelopmental disorders that are thought to share genetic risk factors. However, the identification of definitive susceptibility ...
    • Differential prefrontal gray matter correlates of treatment response to fluoxetine or cognitive-behavioral therapy in obsessive-compulsive disorder 

      Hoexter, Marcelo Q. [UNIFESP]; Dougherty, Darin D.; Shavitt, Roseli G.; D'Alcante, Carina C.; Duran, Fabio L. S.; Lopes, Antonio C.; Diniz, Juliana B.; Batistuzzo, Marcelo C.; Evans, Karleyton C.; Bressan, Rodrigo A. [UNIFESP]; Busatto, Geraldo F.; Miguel, Euripedes C. (Elsevier B.V., 2013-07-01)
      Nearly one-third of patients with obsessive-compulsive disorder (OCD) fail to respond to adequate therapeutic approaches such as serotonin reuptake inhibitors and/or cognitive-behavioral therapy (CBT). This study investigated ...
    • A General Psychopathology Factor (P Factor) in Children: Structural Model Analysis and External Validation Through Familial Risk and Child Global Executive Function 

      Martel, Michelle M.; Pan, Pedro Mario [UNIFESP]; Hoffmann, Mauricio S.; Gadelha, Ary [UNIFESP]; Rosario, Maria Conceicao do [UNIFESP]; Mari, Jair de Jesus [UNIFESP]; Manfro, Gisele G.; Miguel, Euripedes C.; Paus, Tomas; Bressan, Rodrigo Affonseca [UNIFESP]; Rohde, Luis A.; Salum, Giovanni A. (Amer Psychological Assoc, 2017)
      High rates of comorbidities and poor validity of disorder diagnostic criteria for mental disorders hamper advances in mental health research. Recent work has suggested the utility of continuous cross-cutting dimensions, ...
    • 'Impulsive compulsivity' in obsessive-compulsive disorder: A phenotypic marker of patients with poor clinical outcome 

      Kashyap, Himani; Fontenelle, Leonardo F.; Miguel, Euripedes C.; Ferrao, Ygor A.; Torres, Albina R.; Shavitt, Roseli G.; Ferreira-Garcia, Rafael; Rosario, Maria C. do [UNIFESP]; Yuecel, Murat (Elsevier B.V., 2012-09-01)
      Although traditionally obsessive-compulsive disorder (OCD) and impulse control disorders (ICD) have represented opposing ends of a continuum, recent research has demonstrated a frequent co-occurrence of impulsive and ...
    • An Inherited Small Microdeletion at 15q13.3 in a Patient with Early- Onset Obsessive-Compulsive Disorder 

      Cappi, Carolina; Hounie, Ana Gabriela [UNIFESP]; Mariani, Daniel B.; Diniz, Juliana Belo; Silva, Aderbal R. T.; Reis, Viviane N. S.; Busso, Ariane F.; Silva, Amanda Goncalves; Fidalgo, Felipe; Rogatto, Silvia Regina; Miguel, Euripedes C.; Krepischi, Ana C.; Brentani, Helena (Public Library Science, 2014-10-10)
      Copy number variations (CNVs) have been previously associated with several different neurodevelopmen al psychiatric disorders, such as autism, schizophrenia, and attention deficit hyperactivity disorder (ADHD). the present ...
    • International prescribing practices in obsessive-compulsive disorder (OCD) 

      Brakoulias, Vlasios; Starcevic, Vladan; Belloch, Amparo; Dell'Osso, Liliana; Ferrao, Ygor A.; Fontenelle, Leonardo F.; Lochner, Christine; Marazziti, Donatella; Martin, Andrew; Matsunaga, Hisato; Miguel, Euripedes C.; Reddy, Y. C. Janardhan; do Rosario, Maria C. [UNIFESP]; Shavitt, Roseli G.; Sundar, Arumugham Shyam; Stein, Dan Joseph; Viswasam, Kirupamani (Wiley-Blackwell, 2016)
      ObjectivesTo assess rates of psychotropic medication use in patients with obsessive-compulsive disorder (OCD) in seven different countries on five continents and to compare these with international treatment guidelines. ...
    • Late-onset obsessive-compulsive disorder: Risk factors and correlates 

      Frydman, Ilana; Brasil, Pedro E. do; Torres, Albina R.; Shavitt, Roseli G.; Ferrao, Ygor A.; Rosario, Maria C. [UNIFESP]; Miguel, Euripedes C.; Fontenelle, Leonardo F. (Elsevier B.V., 2014-02-01)
      Background: While a great amount of attention has been paid to early-onset obsessive-compulsive disorder (OCD), there is a dearth of studies on patients showing OCD for the first time at later stages of life. in this study, ...
    • Low frequency fluctuation of brain spontaneous activity and obsessive compulsive symptoms in a large school-age sample 

      Hoexter, Marcelo Q.; Biazoli, Claudinei E., Jr.; Alvarenga, Pedro G.; Batistuzzo, Marcelo C.; Salum, Giovanni A.; Gadelha, Ary; Pan, Pedro M.; Anes, Mauricio; Mancini-Martins, Leticia; Moura, Luciana M.; Soriano-Mas, Caries; Aquilla, Marco A. G. Del'; Arnaro, Edson, Jr.; Rohde, Luis A.; Jackowski, Andrea P.; Bressan, Rodrigo A.; Miguel, Euripedes C.; do Rosario, Maria C.; Sato, Joao R. (Pergamon-Elsevier Science Ltd, 2018)
      Background: The present study was designed to explore alterations in brain dynamics at rest that are associated with Obsessive Compulsive Symptoms (OCS) in childhood by measuring low frequency fluctuation of spontaneous ...
    • Obsessive-compulsive symptom dimensions correlate to specific gray matter volumes in treatment-naive patients 

      Alvarenga, Pedro G.; Rosario, Maria C. do [UNIFESP]; Batistuzzo, Marcelo C.; Diniz, Juliana B.; Shavitt, Roseli G.; Duran, Fabio L. S.; Dougherty, Darin D.; Bressan, Rodrigo A. [UNIFESP]; Miguel, Euripedes C.; Hoexter, Marcelo Q. [UNIFESP] (Elsevier B.V., 2012-12-01)
      Background: Clinical and sociodemographic findings have supported that OCD is heterogeneous and composed of multiple potentially overlapping and stable symptom dimensions. Previous neuroimaging investigations have correlated ...
    • Obsessive-compulsive symptom dimensions in a population-based, cross-sectional sample of school-aged children 

      Alvarenga, Pedro G.; Cesar, Raony C.; Leckman, James F.; Moriyama, Tais S.; Torres, Albina R.; Bloch, Michael H.; Coughlin, Catherine G.; Hoexter, Marcelo Q.; Manfro, Gisele G.; Polanczyk, Guilherme V.; Miguel, Euripedes C.; Rosario, Maria C. do [UNIFESP] (Elsevier B.V., 2015-03-01)
      Background: Obsessive-compulsive disorder can be expressed as four potentially overlapping obsessive-compulsive symptom (OCS) dimensions (OCSD) (symmetry/ordering, contamination/cleaning, aggressive/sexual/religious and ...
    • Obsessive-compulsive symptoms are associated with psychiatric comorbidities, behavioral and clinical problems: a population-based study of Brazilian school children 

      Alvarenga, Pedro G.; Rosario, Maria C. do [UNIFESP]; Cesar, Raony C.; Manfro, Gisele G.; Moriyama, Tais S.; Bloch, Michael H.; Shavitt, Roseli G.; Hoexter, Marcelo Q.; Coughlin, Catherine G.; Leckman, James F.; Miguel, Euripedes C. (Springer, 2016)
      Pediatric-onset obsessive-compulsive disorder (OCD) is underdiagnosed, and many affected children are untreated. The present study seeks to evaluate the presence and the clinical impact of OCD and obsessive-compulsive ...
    • Obsessive-compulsive symptoms are associated with psychiatric comorbidities, behavioral and clinical problems: a population-based study of Brazilian school children 

      Alvarenga, Pedro G.; Rosario, Maria C. do [UNIFESP]; Cesar, Raony C.; Manfro, Gisele G.; Moriyama, Tais S.; Bloch, Michael H.; Shavitt, Roseli G.; Hoexter, Marcelo Q.; Coughlin, Catherine G.; Leckman, James F.; Miguel, Euripedes C. (Springer, 2016)
      Pediatric-onset obsessive-compulsive disorder (OCD) is underdiagnosed, and many affected children are untreated. The present study seeks to evaluate the presence and the clinical impact of OCD and obsessive-compulsive ...
    • Panic Disorder and Agoraphobia in OCD patients: Clinical profile and possible treatment implications 

      Torres, Albina R.; Ferrao, Ygor. A.; Shavitt, Roseli G.; Diniz, Juliana B.; Costa, Daniel L. C.; Rosario, Maria Conceicao do [UNIFESP]; Miguel, Euripedes C.; Fontenelle, Leonardo F. (Elsevier B.V., 2014-04-01)
      Objective: Panic Disorder (PD) and agoraphobia (AG) are frequently comorbid with obsessive compulsive disorder (OCD), but the correlates of these comorbidities in OCD are fairly unknown. the study aims were to: 1) estimate ...
    • Partitioning the Heritability of Tourette Syndrome and Obsessive Compulsive Disorder Reveals Differences in Genetic Architecture 

      Davis, Lea K.; Yu, Dongmei; Keenan, Clare L.; Gamazon, Eric R.; Konkashbaev, Anuar I.; Derks, Eske M.; Neale, Benjamin M.; Yang, Jian; Lee, S. Hong; Evans, Patrick; Barr, Cathy L.; Bellodi, Laura; Benarroch, Fortu; Berrio, Gabriel Bedoya; Bienvenu, Oscar J.; Bloch, Michael H.; Blom, Rianne M.; Bruun, Ruth D.; Budman, Cathy L.; Camarena, Beatriz; Campbell, Desmond; Cappi, Carolina; Silgado, Julio C. Cardona; Cath, Danielle C.; Cavallini, Maria C.; Chavira, Denise A.; Chouinard, Sylvain; Conti, David V.; Cook, Edwin H.; Coric, Vladimir; Cullen, Bernadette A.; Deforce, Dieter; Delorme, Richard; Dion, Yves; Edlund, Christopher K.; Egberts, Karin; Falkai, Peter; Fernandez, Thomas V.; Gallagher, Patience J.; Garrido, Helena; Geller, Daniel; Girard, Simon L.; Grabe, Hans J.; Grados, Marco A.; Greenberg, Benjamin D.; Gross-Tsur, Varda; Haddad, Stephen; Heiman, Gary A.; Hemmings, Sian M. J.; Hounie, Ana G.; Illmann, Cornelia; Jankovic, Joseph; Jenike, Michael A.; Kennedy, James L.; King, Robert A.; Kremeyer, Barbara; Kurlan, Roger; Lanzagorta, Nuria; Leboyer, Marion; Leckman, James F.; Lennertz, Leonhard; Liu, Chunyu; Lochner, Christine; Lowe, Thomas L.; Macciardi, Fabio; McCracken, James T.; McGrath, Lauren M.; Restrepo, Sandra C. Mesa; Moessner, Rainald; Morgan, Jubel; Muller, Heike; Murphy, Dennis L.; Naarden, Allan L.; Ochoa, William Cornejo; Ophoff, Roel A.; Osiecki, Lisa; Pakstis, Andrew J.; Pato, Michele T.; Pato, Carlos N.; Piacentini, John; Pittenger, Christopher; Pollak, Yehuda; Rauch, Scott L.; Renner, Tobias J.; Reus, Victor I.; Richter, Margaret A.; Riddle, Mark A.; Robertson, Mary M.; Romero, Roxana; Rosario, Maria C. [UNIFESP]; Rosenberg, David; Rouleau, Guy A.; Ruhrmann, Stephan; Ruiz-Linares, Andres; Sampaio, Aline S.; Samuels, Jack; Sandor, Paul; Sheppard, Brooke; Singer, Harvey S.; Smit, Jan H.; Stein, Dan J.; Strengman, E.; Tischfield, Jay A.; Duarte, Ana V. Valencia; Vallada, Homero; Van Nieuwerburgh, Filip; Veenstra-VanderWeele, Jeremy; Walitza, Susanne; Wang, Ying; Wendland, Jens R.; Westenberg, Herman G. M.; Shugart, Yin Yao; Miguel, Euripedes C.; McMahon, William; Wagner, Michael; Nicolini, Humberto; Posthuma, Danielle; Hanna, Gregory L.; Heutink, Peter; Denys, Damiaan; Arnold, Paul D.; Oostra, Ben A.; Nestadt, Gerald; Freimer, Nelson B.; Pauls, David L.; Wray, Naomi R.; Stewart, S. Evelyn; Mathews, Carol A.; Knowles, James A.; Cox, Nancy J.; Scharf, Jeremiah M. (Public Library Science, 2013-10-01)
      The direct estimation of heritability from genome-wide common variant data as implemented in the program Genome-wide Complex Trait Analysis (GCTA) has provided a means to quantify heritability attributable to all interrogated ...