Transposable elements and two other molecular markers as typing tools for the genus Paracoccidioides

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dc.contributor.authorAlves, Fernanda Lourenco
dc.contributor.authorRibeiro, Mariceli Araujo
dc.contributor.authorHahn, Rosane Christine
dc.contributor.authorTeixeira, Marcus de Melo
dc.contributor.authorCamargo, Zoilo Pires de [UNIFESP]
dc.contributor.authorCisalpino, Patricia Silva
dc.contributor.authorMarini, Marjorie Mendes [UNIFESP]
dc.contributor.institutionUniversidade Federal de Minas Gerais (UFMG)
dc.contributor.institutionUniv Fed Espirito Santo
dc.contributor.institutionUniv Fed Mato Grosso
dc.contributor.institutionUniversidade de Brasília (UnB)
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.date.accessioned2016-01-24T14:40:01Z
dc.date.available2016-01-24T14:40:01Z
dc.date.issued2015-02-01
dc.description.abstractStudies comparing Paracoccidioides brasiliensis and Paracoccidioides lutzii have shown that these fungi have significant genomic differences that may have implications in the clinical manifestation, diagnosis, and treatment of paracoccidioidomycosis caused by them. Thus, molecular typing methods are required that can distinguish between various species of Paracoccidioides. the aim of this study was to explore the potential use as molecular markers of the transposable elements Trem A-H recently identified and characterized in the genus Paracoccidioides as a means of differentiating the species. We take advantage of the abundance and distribution of these transposons in the Paracoccidioides genomes to develop a simple and highly reproducible polymerase chain reaction (PCR)-based technique. Furthermore we compare the performance of this test with two other molecular markers already in use to identify these fungi.en
dc.description.affiliationUniv Fed Minas Gerais, Dept Microbiol, Belo Horizonte, MG, Brazil
dc.description.affiliationUniv Fed Espirito Santo, Ctr Biomed, Dept Patol, Vitoria, ES, Brazil
dc.description.affiliationUniv Fed Mato Grosso, Fac Ciencias Med, Mato Grosso, MT, Brazil
dc.description.affiliationUniv Brasilia, Dept Biol Celular, Inst Ciencias Biol, Brasilia, DF, Brazil
dc.description.affiliationUniversidade Federal de São Paulo, Dept Microbiol Imunol & Parasitol, Disciplina Biol Celular, São Paulo, Brazil
dc.description.affiliationUniversidade Federal de São Paulo, Dept Microbiol Imunol & Parasitol, Disciplina Parasitol, BR-31270901 São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Dept Microbiol Imunol & Parasitol, Disciplina Biol Celular, São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Dept Microbiol Imunol & Parasitol, Disciplina Parasitol, BR-31270901 São Paulo, Brazil
dc.description.sourceWeb of Science
dc.description.sponsorshipCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.format.extent165-170
dc.identifierhttp://dx.doi.org/10.1093/mmy/myu074
dc.identifier.citationMedical Mycology. Oxford: Oxford Univ Press, v. 53, n. 2, p. 165-170, 2015.
dc.identifier.doi10.1093/mmy/myu074
dc.identifier.issn1369-3786
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/38721
dc.identifier.wosWOS:000349745700009
dc.language.isoeng
dc.publisherOxford Univ Press
dc.relation.ispartofMedical Mycology
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.rights.licensehttp://www.oxfordjournals.org/access_purchase/self-archiving_policyb.html
dc.subjecthsp70en
dc.subjectmicrosatellitesen
dc.subjectmolecular typingen
dc.subjectParacoccidioidesen
dc.subjecttransposonsen
dc.titleTransposable elements and two other molecular markers as typing tools for the genus Paracoccidioidesen
dc.typeinfo:eu-repo/semantics/article
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