Generalized anxiety disorder, subthreshold anxiety and anxiety symptoms in primary headache

dc.contributor.authorLucchetti, Giancarlo [UNIFESP]
dc.contributor.authorPeres, Mario F. P. [UNIFESP]
dc.contributor.authorLucchetti, Alessandra L. G.
dc.contributor.authorMercante, Juliane P. P.
dc.contributor.authorGuendler, Vera Z.
dc.contributor.authorZukerman, Eliova
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.contributor.institutionAlbert Einstein Hosp
dc.contributor.institutionGetulio Vargas Fdn
dc.description.abstractAims the aim of the present study was to evaluate the association between generalized anxiety disorder, subthreshold anxiety (SubAnx) and anxiety symptoms in the prevalence of primary headache. Methods This cross-sectional study evaluated 383 people from a Brazilian low-income community. One-year prevalence rates of migraine, chronic migraine and tension-type headache were calculated. Anxiety symptoms were then separated into the following groups (based on DSM-IV criteria): no anxiety criteria; one anxiety criterion; two anxiety criteria; and generalized anxiety disorder (GAD). the control group (no headaches) was compared with headache sufferers for each anxiety group using an adjusted model controlled for confounding factors. Results GAD was present in 37.0% of participants and SubAnx in 16.6%. Those with SubAnx had a 2.28-fold increased chance of having migraine; 3.83-fold increased chance of having chronic migraine, a 5.94-fold increased chance of having tension-type headache and a 3.27-fold increased chance of having overall headache. Some anxiety criteria (irritability, difficulty with sleep, concentration problems, muscle tension and fatigue) had similar prevalence to International Classification of Headache Disorders (ICHD-II) headache criteria such as unilateral pain and nausea for migraine and chronic migraine. Conclusion Headache sufferers seem to have a high prevalence of anxiety symptoms and SubAnx. in addition, the presence of two or more anxiety criteria (not necessarily fulfilling all the criteria for GAD) was associated with having a headache disorder.en
dc.description.affiliationUniversidade Federal de São Paulo, Dept Neurol, BR-01155030 São Paulo, Brazil
dc.description.affiliationAlbert Einstein Hosp, Dept Res, São Paulo, Brazil
dc.description.affiliationGetulio Vargas Fdn, São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Dept Neurol, BR-01155030 São Paulo, Brazil
dc.description.sourceWeb of Science
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.identifier.citationPsychiatry and Clinical Neurosciences. Hoboken: Wiley-Blackwell, v. 67, n. 1, p. 41-49, 2013.
dc.relation.ispartofPsychiatry and Clinical Neurosciences
dc.rightsAcesso aberto
dc.subjectsubthreshold anxietyen
dc.titleGeneralized anxiety disorder, subthreshold anxiety and anxiety symptoms in primary headacheen