Second-generation central venous catheter in the prevention of bloodstream infection: a systematic review

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dc.contributor.authorDorociaki Stocco, Janislei Gislei
dc.contributor.authorHoers, Hellen
dc.contributor.authorPott, Franciele Soares
dc.contributor.authorCrozeta, Karla
dc.contributor.authorBarbosa, Dulce Aparecida [UNIFESP]
dc.contributor.authorMeier, Marineli Joaquim
dc.date.accessioned2019-01-21T10:29:50Z
dc.date.available2019-01-21T10:29:50Z
dc.date.issued2016
dc.description.abstractObjective: to evaluate the effectiveness and safety in the use of second-generation central venous catheters impregnated in clorhexidine and silver sulfadiazine when compared with other catheters, being them impregnated or not, in order to prevent the bloodstream infection prevention. Method: systematic review with meta-analysis. Databases searched: MEDLINE, EMBASE, CINAHL, LILACS/SciELO, Cochrane CENTRALen
dc.description.abstractsearch in Congress Proceedings and records from Clinical Trials. Results: 1.235 studies were identified, 97 were pre-selected and 4 were included. In catheter-related bloodstream infection, there was no statistical significance between second-generation impregnated catheter compared with the non-impregnated ones, absolute relative risk 1,5% confidence interval 95% (3%-1%), relative risk 0,68 (confidence interval 95%, 0,40-1,15) and number needed to treat 66. In the sensitivity analysis, there was less bloodstream infection in impregnated catheters (relative risk 0,50, confidence interval 95%, 0,26-0,96). Lower colonization, absolute relative risk 9,6% (confidence interval 95%, 10% to 4%), relative risk 0,51 (confidence interval 95% from 0,38-0,85) and number needed to treat 5. Conclusion: the use of second-generation catheters was effective in reducing the catheter colonization and infection when a sensitivity analysis is performed. Future clinical trials are suggested to evaluate sepsis rates, mortality and adverse effects.en
dc.description.affiliationHospital de Clínicas, Universidade Federal do Paraná, Curitiba, PR, Brazil
dc.description.affiliationDepartamento de Enfermagem, Universidade Federal do Paraná, Curitiba, PR, Brazil
dc.description.affiliationUniversidade Federal do Paraná, Curitiba, PR, Brasil. RN, Secretaria Estadual de Segurança Pública, Curitiba, PR, Brazil
dc.description.affiliationEscola Paulista de Enfermagem, Universidade Federal de São Paulo, São Paulo, SP, Brazil
dc.description.affiliationUnifespEscola Paulista de Enfermagem, Universidade Federal de São Paulo, São Paulo, SP, Brazil
dc.description.sourceWeb of Science
dc.format.extente2722
dc.identifierhttp://dx.doi.org/10.1590/1518-8345.0756.2722
dc.identifier.citationRevista Latino-Americana De Enfermagem. Ribeirao preto, v. 24, p. e2722, 2016.
dc.identifier.doi10.1590/1518-8345.0756.2722
dc.identifier.fileS0104-11692016000100605.pdf
dc.identifier.issn1518-8345
dc.identifier.scieloS0104-11692016000100605
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/49428
dc.identifier.wosWOS:000380887900028
dc.language.isoeng
dc.publisherSoc Brasil Pediatria
dc.relation.ispartofRevista Latino-Americana De Enfermagem
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectCatheterization, Central Venousen
dc.subjectCatheter-Related Infectionen
dc.subjectColonizationen
dc.subjectSepsisen
dc.subjectMeta-AnalysisSilver-Sulfadiazineen
dc.subjectControlled-Trialen
dc.subjectChlorhexidineen
dc.subjectGuidelinesen
dc.subjectHospitalsen
dc.titleSecond-generation central venous catheter in the prevention of bloodstream infection: a systematic reviewen
dc.typeinfo:eu-repo/semantics/article
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