Worse renal transplant outcomes observed among Afro-Brazilian patients on prospective registry data of 2461 renal transplants at least 1 year follow-up

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dc.contributor.authorMedina-Pestana, J. O.
dc.contributor.authorSampaio, E. M.
dc.contributor.authorVaz, M. L. S.
dc.contributor.authorPinheiro-Machado, P. G.
dc.contributor.authorTedesco-Silva, H.
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.date.accessioned2016-01-24T12:41:57Z
dc.date.available2016-01-24T12:41:57Z
dc.date.issued2007-03-01
dc.description.abstractWe present prospective registry data of 2461 (live donor = 1753 and deceased donor = 08) renal transplants performed between 1999 and 2003. All subjects were followed for more than 1 year after transplantation and most were treated with a calcineurin inhibitor and azathioprine. Afro-Brazilian, white, and mixed patients constituted 11% (272), 67.1% (1651), and 14.9% (367) of the population respectively. Mean dialysis time was 42.3 +/- 32.9 months and delayed graft function, occurred in more than 60%. Three-year patient survival rates were 96.3%, 92.8%, and 86.7% for living-related, living-unrelated, and deceased donors, respectively. Corresponding 3-year graft survival rates were 87.3%, 82.1%, and 71.3% and functional graft survival rates were 90.2%, 88.8%, and 81.5%. the poorer transplant outcome observed among Afro-Brazilian patients has been mainly attributed to differences in absorption of cyclosporine, tacrolimus, and mycophenolate mofetil.en
dc.description.affiliationUniversidade Federal de São Paulo, Hosp Rim & Hipertensao, Div Nephrol, São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Hosp Rim & Hipertensao, Div Nephrol, São Paulo, Brazil
dc.description.sourceWeb of Science
dc.format.extent435-436
dc.identifierhttp://dx.doi.org/10.1016/j.transproceed.2007.01.034
dc.identifier.citationTransplantation Proceedings. New York: Elsevier B.V., v. 39, n. 2, p. 435-436, 2007.
dc.identifier.doi10.1016/j.transproceed.2007.01.034
dc.identifier.issn0041-1345
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/29566
dc.identifier.wosWOS:000245344200032
dc.language.isoeng
dc.publisherElsevier B.V.
dc.relation.ispartofTransplantation Proceedings
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.rights.licensehttp://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
dc.titleWorse renal transplant outcomes observed among Afro-Brazilian patients on prospective registry data of 2461 renal transplants at least 1 year follow-upen
dc.typeinfo:eu-repo/semantics/article
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